A mathematical model of regional citrate anticoagulation in hemodialysis

Thijssen, StephanStephanThijssenKruse, AnjaAnjaKruseRaimann, JochenJochenRaimannBhalani, VirajVirajBhalaniLevin, Nathan WNathan WLevinKotanko, PeterPeterKotanko2024-10-102024-10-102010https://boris-portal.unibe.ch/handle/20.500.12422/72515Regional citrate anticoagulation (RCA) during hemodialysis (HD) has several advantages over heparin anticoagulation, but calcium (Ca) derangements are a major concern necessitating repeated monitoring of systemic ionized Ca (Ca(2+)). We developed a mathematical model of Ca and citrate (Ci) kinetics during RCA.enA mathematical model of regional citrate anticoagulation in hemodialysisarticle10.48350/18002009382700027354670002110.1159/000245647