Galluzzi, LorenzoLorenzoGalluzziVitale, IlioIlioVitaleAaronson, Stuart AStuart AAaronsonAbrams, John MJohn MAbramsAdam, DieterDieterAdamAgostinis, PatriziaPatriziaAgostinisAlnemri, Emad SEmad SAlnemriAltucci, LuciaLuciaAltucciAmelio, IvanoIvanoAmelioAndrews, David WDavid WAndrewsAnnicchiarico-Petruzzelli, MargheritaMargheritaAnnicchiarico-PetruzzelliAntonov, Alexey VAlexey VAntonovArama, EliEliAramaBaehrecke, Eric HEric HBaehreckeBarlev, Nickolai ANickolai ABarlevBazan, Nicolas GNicolas GBazanBernassola, FrancescaFrancescaBernassolaBertrand, Mathieu J MMathieu J MBertrandBianchi, KatiusciaKatiusciaBianchiBlagosklonny, Mikhail VMikhail VBlagosklonnyBlomgren, KlasKlasBlomgrenBorner, ChristophChristophBornerBoya, PatriciaPatriciaBoyaBrenner, CatherineCatherineBrennerCampanella, MichelangeloMichelangeloCampanellaCandi, EleonoraEleonoraCandiCarmona-Gutierrez, DidacDidacCarmona-GutierrezCecconi, FrancescoFrancescoCecconiChan, Francis K-MFrancis K-MChanChandel, Navdeep SNavdeep SChandelCheng, Emily HEmily HChengChipuk, Jerry EJerry EChipukCidlowski, John AJohn ACidlowskiCiechanover, AaronAaronCiechanoverCohen, Gerald MGerald MCohenConrad, MarcusMarcusConradCubillos-Ruiz, Juan RJuan RCubillos-RuizCzabotar, Peter EPeter ECzabotarD'Angiolella, VincenzoVincenzoD'AngiolellaDawson, Ted MTed MDawsonDawson, Valina LValina LDawsonDe Laurenzi, VincenzoVincenzoDe LaurenziDe Maria, RuggeroRuggeroDe MariaDebatin, Klaus-MichaelKlaus-MichaelDebatinDeBerardinis, Ralph JRalph JDeBerardinisDeshmukh, MohanishMohanishDeshmukhDi Daniele, NicolaNicolaDi DanieleDi Virgilio, FrancescoFrancescoDi VirgilioDixit, Vishva MVishva MDixitDixon, Scott JScott JDixonDuckett, Colin SColin SDuckettDynlacht, Brian DBrian DDynlachtEl-Deiry, Wafik SWafik SEl-DeiryElrod, John WJohn WElrodFimia, Gian MariaGian MariaFimiaFulda, SimoneSimoneFuldaGarcía-Sáez, Ana JAna JGarcía-SáezGarg, Abhishek DAbhishek DGargGarrido, CarmenCarmenGarridoGavathiotis, EvripidisEvripidisGavathiotisGolstein, PierrePierreGolsteinGottlieb, EyalEyalGottliebGreen, Douglas RDouglas RGreenGreene, Lloyd ALloyd AGreeneGronemeyer, HinrichHinrichGronemeyerGross, AtanAtanGrossHajnoczky, GyorgyGyorgyHajnoczkyHardwick, J MarieJ MarieHardwickHarris, Isaac SIsaac SHarrisHengartner, Michael OMichael OHengartnerHetz, ClaudioClaudioHetzIchijo, HidenoriHidenoriIchijoJäättelä, MarjaMarjaJäätteläJoseph, BertrandBertrandJosephJost, Philipp JPhilipp JJostJuin, Philippe PPhilippe PJuinKaiser, William JWilliam JKaiserKarin, MichaelMichaelKarinKaufmann, ThomasThomasKaufmann0000-0001-9906-874XKepp, OliverOliverKeppKimchi, AdiAdiKimchiKitsis, Richard NRichard NKitsisKlionsky, Daniel JDaniel JKlionskyKnight, Richard ARichard AKnightKumar, SharadSharadKumarLee, Sam WSam WLeeLemasters, John JJohn JLemastersLevine, BethBethLevineLinkermann, AndreasAndreasLinkermannLipton, Stuart AStuart ALiptonLockshin, Richard ARichard ALockshinLópez-Otín, CarlosCarlosLópez-OtínLowe, Scott WScott WLoweLuedde, TomTomLueddeLugli, EnricoEnricoLugliMacFarlane, MarionMarionMacFarlaneMadeo, FrankFrankMadeoMalewicz, MichalMichalMalewiczMalorni, WalterWalterMalorniManic, GwenolaGwenolaManicMarine, Jean-ChristopheJean-ChristopheMarineMartin, Seamus JSeamus JMartinMartinou, Jean-ClaudeJean-ClaudeMartinouMedema, Jan PaulJan PaulMedemaMehlen, PatrickPatrickMehlenMeier, PascalPascalMeierMelino, SoniaSoniaMelinoMiao, Edward AEdward AMiaoMolkentin, Jeffery DJeffery DMolkentinMoll, Ute MUte MMollMuñoz-Pinedo, CristinaCristinaMuñoz-PinedoNagata, ShigekazuShigekazuNagataNuñez, GabrielGabrielNuñezOberst, AndrewAndrewOberstOren, MosheMosheOrenOverholtzer, MichaelMichaelOverholtzerPagano, MicheleMichelePaganoPanaretakis, TheocharisTheocharisPanaretakisPasparakis, ManolisManolisPasparakisPenninger, Josef MJosef MPenningerPereira, David MDavid MPereiraPervaiz, ShazibShazibPervaizPeter, Marcus EMarcus EPeterPiacentini, MauroMauroPiacentiniPinton, PaoloPaoloPintonPrehn, Jochen H MJochen H MPrehnPuthalakath, HamsaHamsaPuthalakathRabinovich, Gabriel AGabriel ARabinovichRehm, MarkusMarkusRehmRizzuto, RosarioRosarioRizzutoRodrigues, Cecilia M PCecilia M PRodriguesRubinsztein, David CDavid CRubinszteinRudel, ThomasThomasRudelRyan, Kevin MKevin MRyanSayan, EmreEmreSayanScorrano, LucaLucaScorranoShao, FengFengShaoShi, YufangYufangShiSilke, JohnJohnSilkeSimon, Hans-UweHans-UweSimon0000-0002-9404-7736Sistigu, AntonellaAntonellaSistiguStockwell, Brent RBrent RStockwellStrasser, AndreasAndreasStrasserSzabadkai, GyorgyGyorgySzabadkaiTait, Stephen W GStephen W GTaitTang, DaolinDaolinTangTavernarakis, NektariosNektariosTavernarakisThorburn, AndrewAndrewThorburnTsujimoto, YoshihideYoshihideTsujimotoTurk, BorisBorisTurkVanden Berghe, TomTomVanden BergheVandenabeele, PeterPeterVandenabeeleVander Heiden, Matthew GMatthew GVander HeidenVillunger, AndreasAndreasVillungerVirgin, Herbert WHerbert WVirginVousden, Karen HKaren HVousdenVucic, DomagojDomagojVucicWagner, Erwin FErwin FWagnerWalczak, HenningHenningWalczakWallach, DavidDavidWallachWang, YingYingWangWells, James AJames AWellsWood, WillWillWoodYuan, JunyingJunyingYuanZakeri, ZahraZahraZakeriZhivotovsky, BorisBorisZhivotovskyZitvogel, LaurenceLaurenceZitvogelMelino, GerryGerryMelinoKroemer, GuidoGuidoKroemer2024-10-252024-10-252018-03https://boris-portal.unibe.ch/handle/20.500.12422/158858Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from morphological, biochemical, and functional perspectives. Since the field continues to expand and novel mechanisms that orchestrate multiple cell death pathways are unveiled, we propose an updated classification of cell death subroutines focusing on mechanistic and essential (as opposed to correlative and dispensable) aspects of the process. As we provide molecularly oriented definitions of terms including intrinsic apoptosis, extrinsic apoptosis, mitochondrial permeability transition (MPT)-driven necrosis, necroptosis, ferroptosis, pyroptosis, parthanatos, entotic cell death, NETotic cell death, lysosome-dependent cell death, autophagy-dependent cell death, immunogenic cell death, cellular senescence, and mitotic catastrophe, we discuss the utility of neologisms that refer to highly specialized instances of these processes. The mission of the NCCD is to provide a widely accepted nomenclature on cell death in support of the continued development of the field.en600 - Technology::610 - Medicine & healtharticle10.7892/boris.1120252936247910.1038/s41418-017-0012-4