Alderson, LiliLiliAldersonWakeford, Hannah RHannah RWakefordAlam, Munazza KMunazza KAlamBatalha, Natasha ENatasha EBatalhaLothringer, Joshua DJoshua DLothringerRedai, Jea AdamsJea AdamsRedaiBarat, SaugataSaugataBaratBrande, JonathanJonathanBrandeDamiano, MarioMarioDamianoDaylan, TansuTansuDaylanEspinoza, NéstorNéstorEspinozaFlagg, LauraLauraFlaggGoyal, Jayesh MJayesh MGoyalGrant, DavidDavidGrantHu, RenyuRenyuHuInglis, JulieJulieInglisLee, ElspethElspethLee0000-0002-3052-7116Mikal-Evans, ThomasThomasMikal-EvansRamos-Rosado, LakeishaLakeishaRamos-RosadoRoy, Pierre-AlexisPierre-AlexisRoyWallack, Nicole LNicole LWallackBatalha, Natalie MNatalie MBatalhaBean, Jacob LJacob LBeanBenneke, BjörnBjörnBennekeBerta-Thompson, Zachory KZachory KBerta-ThompsonCarter, Aarynn LAarynn LCarterChangeat, QuentinQuentinChangeatColón, Knicole DKnicole DColónCrossfield, Ian J MIan J MCrossfieldDésert, Jean-MichelJean-MichelDésertForeman-Mackey, DanielDanielForeman-MackeyGibson, Neale PNeale PGibsonKreidberg, LauraLauraKreidbergLine, Michael RMichael RLineLópez-Morales, MercedesMercedesLópez-MoralesMolaverdikhani, KaranKaranMolaverdikhaniMoran, Sarah ESarah EMoranMorello, GiuseppeGiuseppeMorelloMoses, Julianne IJulianne IMosesMukherjee, SagnickSagnickMukherjeeSchlawin, EverettEverettSchlawinSing, David KDavid KSingStevenson, Kevin BKevin BStevensonTaylor, JakeJakeTaylorAggarwal, KeshavKeshavAggarwalAhrer, Eva-MariaEva-MariaAhrerAllen, Natalie HNatalie HAllenBarstow, Joanna KJoanna KBarstowBell, Taylor JTaylor JBellBlecic, JasminaJasminaBlecicCasewell, Sarah LSarah LCasewellChubb, Katy LKaty LChubbCrouzet, NicolasNicolasCrouzetCubillos, Patricio EPatricio ECubillosDecin, LeenLeenDecinFeinstein, Adina DAdina DFeinsteinFortney, Joanthan JJoanthan JFortneyHarrington, JosephJosephHarringtonHeng, KevinKevinHengIro, NicolasNicolasIroKempton, Eliza M-REliza M-RKemptonKirk, JamesJamesKirkKnutson, Heather AHeather AKnutsonKrick, JessicaJessicaKrickLeconte, JérémyJérémyLeconteLendl, MonikaMonikaLendlMacDonald, Ryan JRyan JMacDonaldMancini, LuigiLuigiManciniMansfield, MeganMeganMansfieldMay, Erin MErin MMayMayne, Nathan JNathan JMayneMiguel, YamilaYamilaMiguelNikolov, Nikolay KNikolay KNikolovOhno, KazumasaKazumasaOhnoPalle, EnricEnricPalleParmentier, VivienVivienParmentierPetit Dit de la Roche, Dominique J MDominique J MPetit Dit de la RochePiaulet, CarolineCarolinePiauletPowell, DianaDianaPowellRackham, Benjamin VBenjamin VRackhamRedfield, SethSethRedfieldRogers, Laura KLaura KRogersRustamkulov, ZafarZafarRustamkulovTan, XianyuXianyuTanTremblin, PPTremblinTsai, Shang-MinShang-MinTsaiTurner, Jake DJake DTurnerde Val-Borro, MiguelMiguelde Val-BorroVenot, OliviaOliviaVenotWelbanks, LuisLuisWelbanksWheatley, Peter JPeter JWheatleyZhang, XiXiZhang2024-10-152024-10-152023-02https://boris-portal.unibe.ch/handle/20.500.12422/120322Measuring the abundances of carbon and oxygen in exoplanet atmospheres is considered a crucial avenue for unlocking the formation and evolution of exoplanetary systems1,2. Access to an exoplanet's chemical inventory requires high precision observations, often inferred from individual molecular detections with low-resolution space-based3-5 and high-resolution ground-based6-8 facilities. Here we report the medium-resolution (R≈600) transmission spectrum of an exoplanet atmosphere between 3-5 μm covering multiple absorption features for the Saturn-mass exoplanet WASP-39b9, obtained with JWST NIRSpec G395H. Our observations achieve 1.46[Formula: see text] photon precision, providing an average transit depth uncertainty of 221 ppm per spectroscopic bin, and present minimal impacts from systematic effects. We detect significant absorption from CO2 (28.5[Formula: see text]) and H2O (21.5[Formula: see text]), and identify SO2 as the source of absorption at 4.1 [Formula: see text]m (4.8[Formula: see text]). Best-fit atmospheric models range between 3[Formula: see text] and 10[Formula: see text] solar metallicity, with sub-solar to solar C/O ratios. These results, including the detection of SO2, underscore the importance of characterising the chemistry in exoplanet atmospheres, and showcase NIRSpec G395H as an excellent mode for time series observations over this critical wavelength range10.en500 - Science500 - Science::520 - Astronomy500 - Science::530 - Physicsarticle10.48350/1771353662354910.1038/s41586-022-05591-3