Thiede, JanJanThiede0000-0003-1842-9975Rothenbühler, SimonSimonRothenbühler0000-0002-6212-2295Iacovache, Mircea IoanMircea IoanIacovacheLangenegger, Simon MatthiasSimon MatthiasLangeneggerZuber, BenoîtBenoîtZuber0000-0001-7725-5579Häner, RobertRobertHäner0000-0001-5014-43182024-10-252024-10-252023-10-11https://boris-portal.unibe.ch/handle/20.500.12422/170242The supramolecular self-assembly of pyrene-DNA conjugates into nanostructures is presented. DNA functionalized with different types of pyrene isomers at the 3'-end self-assemble into nano-objects. The shape of the nanostructures is influenced by the type of pyrene isomer appended to the DNA. Multilamellar vesicles are observed with the 1,6- and 1,8-isomers, whereas conjugates of the 2,7-isomer exclusively assemble into spherical nanoparticles. Self-assembled nano-spheres obtained with the 2,7-dialkynyl pyrene isomer were used for the construction of an artificial light-harvesting complex (LHC) in combination with Cy3 as the energy acceptor.en500 - Science::570 - Life sciences; biology500 - Science::540 - Chemistry600 - Technology::610 - Medicine & healtharticle10.48350/1866303775081110.1039/d3ob01375h