Abril Gaona, CarlosCarlosAbril GaonaBrodard, IsabelleIsabelleBrodardPerreten, VincentVincentPerreten0000-0001-5722-94452024-10-112024-10-112010https://boris-portal.unibe.ch/handle/20.500.12422/82445New tetracycline and streptomycin resistance genes, tet(44) and ant(6)-Ib, were identified in Campylobacter fetus subsp. fetus within a transferable pathogenicity island that is typically unique to Campylobacter fetus subsp. venerealis. The 640-amino-acid tetracycline resistance determinant, Tet 44, belongs to a class of proteins that confers resistance to tetracycline and minocycline by ribosomal protection. The 286-amino-acid streptomycin resistance determinant, ANT(6)-Ib, belongs to a family of aminoglycoside nucleotidyltransferases. The resistance phenotypes were demonstrated by gene inactivation and expression.en500 - Science::570 - Life sciences; biology600 - Technology::610 - Medicine & health600 - Technology::630 - Agriculturearticle10.7892/boris.1233800027884510004710.1128/AAC.00304-10