Ming, Xiu-FenXiu-FenMingRajapakse, Angana GAngana GRajapakseYepuri, GauthamGauthamYepuriXiong, YuyanYuyanXiongCarvas, João MJoão MCarvasRuffieux, JeanJeanRuffieuxScerri, IsabelleIsabelleScerriWu, ZongsongZongsongWuPopp, KatjaKatjaPoppLi, JianhuiJianhuiLiSartori, ClaudioClaudioSartoriScherrer, UrsUrsScherrerKwak, Brenda RBrenda RKwakMontani, Jean-PierreJean-PierreMontaniYang, ZhihongZhihongYang2024-10-132024-10-132012https://boris-portal.unibe.ch/handle/20.500.12422/89356Macrophage-mediated chronic inflammation is mechanistically linked to insulin resistance and atherosclerosis. Although arginase I is considered antiinflammatory, the role of arginase II (Arg-II) in macrophage function remains elusive. This study characterizes the role of Arg-II in macrophage inflammatory responses and its impact on obesity-linked type II diabetes mellitus and atherosclerosis.enarticle23130157