Tang, M MM MTangSpanou, ZoiZoiSpanouTang, HHTangSchibler, FFSchiblerPelivani, NedzmidinNedzmidinPelivaniYawalkar, NNYawalkar2024-10-132024-10-132012https://boris-portal.unibe.ch/handle/20.500.12422/89543Generalized pustular psoriasis (GPP) is a severe inflammatory disease characterized by recurrent eruptions of sterile pustules on erythematous skin. Although tumor necrosis factor (TNF) antagonists may lead to a rapid resolution of GPP, the mechanism of action of these agents remains to be investigated. Here, we sought to evaluate markers of immune response in the skin of a patient who experienced a rapid amelioration of GPP after treatment with infliximab and acitretin.enRapid downregulation of innate immune cells, interleukin-12 and interleukin-23 in generalized pustular psoriasis with infliximab in combination with acitretinarticle10.48350/154932334361100031597630000910.1159/000346243