Benzing, Valentin JohannesValentin JohannesBenzing0000-0002-9940-5635Siegwart, ValerieValerieSiegwartSpitzhüttl, Janine SophieJanine SophieSpitzhüttlSchmid, JürgJürgSchmid0000-0002-6265-7660Grotzer, MichaelMichaelGrotzerRoebers, ClaudiaClaudiaRoebersSteinlin, MajaMajaSteinlinLeibundgut, KurtKurtLeibundgutEverts, RegulaRegulaEvertsSchmidt, MirkoMirkoSchmidt0000-0003-4859-65472024-10-312024-10-312021-03https://boris-portal.unibe.ch/handle/20.500.12422/188401Background: Cancer survivorship is frequently associated with severe late effects. However, research into pediatric cancer survivors on late effects in motor ability, physical self-concept and their relationship to quality of life is limited. Methods: Using multiple regression analyses, 78 pediatric cancer survivors and 56 typically developing children were compared in motor ability, physical self-concept and health-related quality of life. In addition, mediational multi-group analyses between motor ability (independent variable), physical self-concept (mediator) and quality of life (dependent variable) were calculated. Results: Pediatric cancer survivors had a lower motor ability (gHedges = 0.863), a lower physical self-concept with regard to several scales of the PSDQ-S (gHedges = 0.318-0.764) and a higher relative risk for a below average quality of life than controls (RR = 1.44). Children with a history of cancer involving the central nervous system showed poorer motor ability compared to those without central nervous system involvement (gHedges = 0.591). Furthermore, the physical self-concept significantly mediated the relationship between motor ability and quality of life in pediatric cancer survivors but not in typically developing children. Conclusions: Results show the importance of monitoring and supporting the development of motor ability in the aftercare of pediatric cancer survivors. Physical activity interventions may be advisable to prevent physical activity-related late effects and potentially improve related psychosocial variables such as quality of life.en700 - Arts::790 - Sports, games & entertainment600 - Technology::610 - Medicine & health100 - Philosophy::150 - Psychologyarticle10.48350/1514473352776810.1002/cam4.3750