Miran, BayadBayadMiranToneatti, Daniel J.Daniel J.ToneattiSchaller, BenoîtBenoîtSchallerKalaitsidou, IoannaIoannaKalaitsidou2025-12-232025-12-232025-11-27https://boris-portal.unibe.ch/handle/20.500.12422/225618Background/Objectives: Isolated orbital floor fractures are a common consequence of midfacial trauma and are frequently associated with functional and aesthetic complications such as diplopia, enophthalmos, infraorbital hypoesthesia, restricted ocular motility, and, in rare cases, blindness. Current therapeutic approaches vary significantly between different surgeons. This systematic review aimed to evaluate different treatment strategies for isolated orbital floor fractures to determine the most effective approaches. Methods: Electronic systematic searches were conducted using keywords to identify studies reporting isolated orbital floor fractures. Publications were screened for eligibility, and relevant data were extracted and evaluated. Results: This systematic review included 444 patients from 27 selected studies. 42 patients were treated conservatively, while 381 underwent various surgical interventions. Overall, the mentioned treatment modalities were successful in correcting enophthalmos (85.2%), diplopia (74.8%), ocular motility restriction (61.6%), and sensory disturbances (61.1%) in their respective patient cohorts. The complication and reoperation rates for the surgical interventions were low during the follow-up periods ranging from 6 weeks to 10 years. The timing, surgical approach, and reconstructive technique varied widely across the studies. Conclusions: Both conservative and surgical management of isolated orbital floor fractures can achieve satisfactory clinical outcomes. Clinical symptoms, defect size, and the surgeon's preference define the ideal treatment modality.enbiocompatible materialsmaxillofacial injuriesoperativeorbitorbital reconstructionsurgical proceduressystematic review600 - Technology::610 - Medicine & healtharticle10.48620/933694137440510.3390/diagnostics15233024