Fountoulakis, Konstantinos N.Konstantinos N.FountoulakisKarakatsoulis, Grigorios N.Grigorios N.KarakatsoulisAbraham, SeriSeriAbrahamAdorjan, KristinaKristinaAdorjanAhmed, Helal UddinHelal UddinAhmedAlarcón, Renato D.Renato D.AlarcónArai, KiyomiKiyomiAraiAuwal, Sani SalihuSani SalihuAuwalBerk, MichaelMichaelBerkBjedov, SarahSarahBjedovBobes, JulioJulioBobesBobes-Bascaran, TeresaTeresaBobes-BascaranBourgin-Duchesnay, JulieJulieBourgin-DuchesnayBredicean, Cristina AnaCristina AnaBrediceanBukelskis, LaurynasLaurynasBukelskisBurkadze, AkakiAkakiBurkadzeCabrera Abud, Indira IndianaIndira IndianaCabrera AbudCastilla-Puentes, RubyRubyCastilla-PuentesCetkovich, MarceloMarceloCetkovichColon-Rivera, HectorHectorColon-RiveraCorral, RicardoRicardoCorralCortez-Vergara, CarlaCarlaCortez-VergaraCrepin, PiirikaPiirikaCrepinDe Berardis, DomenicoDomenicoDe BerardisZamora Delgado, SergioSergioZamora DelgadoLucena, David DeDavid DeLucenaSousa, Avinash DeAvinash DeSousaStefano, Ramona DiRamona DiStefanoDodd, SeetalSeetalDoddPriyanka Elek, LiviaLiviaPriyanka ElekElissa, AnnaAnnaElissaErdelyi-Hamza, BertaBertaErdelyi-HamzaErzin, GamzeGamzeErzinEtchevers, Martin J.Martin J.EtcheversFalkai, PeterPeterFalkaiFarcas, AdrianaAdrianaFarcasFedotov, IlyaIlyaFedotovFilatova, ViktoriiaViktoriiaFilatovaFountoulakis, Nikolaos K.Nikolaos K.FountoulakisFrankova, IrynaIrynaFrankovaFranza, FrancescoFrancescoFranzaFrias, PedroPedroFriasGalako, TatianaTatianaGalakoGaray, Cristian J.Cristian J.GarayGarcia-Álvarez, LeticiaLeticiaGarcia-ÁlvarezGarcía-Portilla, Maria PazMaria PazGarcía-PortillaGonda, XeniaXeniaGondaGondek, Tomasz M.Tomasz M.GondekMorera González, DanielaDanielaMorera GonzálezGould, HilaryHilaryGouldGrandinetti, PaoloPaoloGrandinettiGrau, ArturoArturoGrauGroudeva, VioletaVioletaGroudevaHagin, MichalMichalHaginHarada, TakayukiTakayukiHaradaHasan, Tasdik M.Tasdik M.HasanAzreen Hashim, NurulNurulAzreen HashimHilbig, JanJanHilbigHossain, SahadatSahadatHossainIakimova, RossitzaRossitzaIakimovaIbrahim, MonaMonaIbrahimIftene, FeliciaFeliciaIfteneIgnatenko, YuliaYuliaIgnatenkoIrarrazaval, MatiasMatiasIrarrazavalIsmail, ZalihaZalihaIsmailIsmayilova, JamilaJamilaIsmayilovaJakobs, AsafAsafJakobsJakovljević, MiroMiroJakovljevićJakšić, NenadNenadJakšićJaved, AfzalAfzalJavedKafali, Helin YilmazHelin YilmazKafaliKaria, SagarSagarKariaKazakova, OlgaOlgaKazakovaKhalifa, DoaaDoaaKhalifaKhaustova, OlenaOlenaKhaustovaKoh, SteveSteveKohKopishinskaia, SvetlanaSvetlanaKopishinskaiaKosenko, KorneliiaKorneliiaKosenkoKoupidis, Sotirios A.Sotirios A.KoupidisKovacs, IllesIllesKovacsKulig, BarbaraBarbaraKuligLalljee, AlishaAlishaLalljeeLiewig, JustineJustineLiewigMajid, AbdulAbdulMajidMalashonkova, EvgeniiaEvgeniiaMalashonkovaMalik, KhameliaKhameliaMalikMalik, Najma IqbalNajma IqbalMalikMammadzada, GulayGulayMammadzadaMandalia, BilveshBilveshMandaliaMarazziti, DonatellaDonatellaMarazzitiMarčinko, DarkoDarkoMarčinkoMartinez, StephanieStephanieMartinezMatiekus, EimantasEimantasMatiekusMejia, GabrielaGabrielaMejiaMemon, Roha SaeedRoha SaeedMemonMeza Martínez, Xarah ElenneXarah ElenneMeza MartínezMickevičiūtė, DaliaDaliaMickevičiūtėMilev, RoumenRoumenMilevMohammed, MuftauMuftauMohammedMolina-López, AlejandroAlejandroMolina-LópezMorozov, PetrPetrMorozovMuhammad, Nuru SuleimanNuru SuleimanMuhammadMustač, FilipFilipMustačNaor, Mika S.Mika S.NaorNassieb, AmiraAmiraNassiebNavickas, AlvydasAlvydasNavickasOkasha, TarekTarekOkashaPandova, MilenaMilenaPandovaPanfil, Anca-LiviaAnca-LiviaPanfilPanteleeva, LiliyaLiliyaPanteleevaPapava, IonIonPapavaPatsali, Mikaella E.Mikaella E.PatsaliPavlichenko, AlexeyAlexeyPavlichenkoPejuskovic, BojanaBojanaPejuskovicPinto Da Costa, MarianaMarianaPinto Da CostaPopkov, MikhailMikhailPopkovPopovic, DinaDinaPopovicRaduan, Nor Jannah NasutionNor Jannah NasutionRaduanVargas Ramírez, FranciscaFranciscaVargas RamírezRancans, ElmarsElmarsRancansRazali, SalmiSalmiRazaliRebok, FedericoFedericoRebokRewekant, AnnaAnnaRewekantNinoska Reyes Flores, ElenaElenaNinoska Reyes FloresRivera-Encinas, María TeresaMaría TeresaRivera-EncinasSaiz, PilarPilarSaizSánchez de Carmona, ManuelManuelSánchez de CarmonaSaucedo Martínez, DavidDavidSaucedo MartínezSaw, Jo AnneJo AnneSawSaygili, GörkemGörkemSaygiliSchneidereit, PatriciaPatriciaSchneidereitShah, BhumikaBhumikaShahShirasaka, TomohiroTomohiroShirasakaSilagadze, KetevanKetevanSilagadzeSitanggang, SattiSattiSitanggangSkugarevsky, OlegOlegSkugarevskySpikina, AnnaAnnaSpikinaMahalingappa, Sridevi SiraSridevi SiraMahalingappaStoyanova, MariaMariaStoyanovaSzczegielniak, AnnaAnnaSzczegielniakTamasan, Simona ClaudiaSimona ClaudiaTamasanTavormina, GiuseppeGiuseppeTavorminaTavormina, Maurilio Giuseppe MariaMaurilio Giuseppe MariaTavorminaTheodorakis, Pavlos N.Pavlos N.TheodorakisTohen, MauricioMauricioTohenTsapakis, Eva MariaEva MariaTsapakisTukhvatullina, DinaDinaTukhvatullinaUllah, IrfanIrfanUllahVaidya, RatnarajRatnarajVaidyaVega-Dienstmaier, Johann M.Johann M.Vega-DienstmaierVrublevska, JelenaJelenaVrublevskaVukovic, OliveraOliveraVukovicVysotska, OlgaOlgaVysotskaWidiasih, NataliaNataliaWidiasihYashikhina, AnnaAnnaYashikhinaPrezerakos, Panagiotis E.Panagiotis E.PrezerakosSmirnova, DariaDariaSmirnova2025-06-022025-06-022024-01-25https://boris-portal.unibe.ch/handle/20.500.12422/211352<jats:title>Abstract</jats:title><jats:sec id="S1092852924000026_sec1"><jats:title>Background</jats:title><jats:p>The prevalence of medical illnesses is high among patients with psychiatric disorders. The current study aimed to investigate multi-comorbidity in patients with psychiatric disorders in comparison to the general population. Secondary aims were to investigate factors associated with metabolic syndrome and treatment appropriateness of mental disorders.</jats:p></jats:sec><jats:sec id="S1092852924000026_sec2" sec-type="methods"><jats:title>Methods</jats:title><jats:p>The sample included 54,826 subjects (64.73% females; 34.15% males; 1.11% nonbinary gender) from 40 countries (COMET-G study). The analysis was based on the registration of previous history that could serve as a fair approximation for the lifetime prevalence of various medical conditions.</jats:p></jats:sec><jats:sec id="S1092852924000026_sec3" sec-type="results"><jats:title>Results</jats:title><jats:p>About 24.5% reported a history of somatic and 26.14% of mental disorders. Mental disorders were by far the most prevalent group of medical conditions. Comorbidity of any somatic with any mental disorder was reported by 8.21%. One-third to almost two-thirds of somatic patients were also suffering from a mental disorder depending on the severity and multicomorbidity. Bipolar and psychotic patients and to a lesser extent depressives, manifested an earlier (15–20 years) manifestation of somatic multicomorbidity, severe disability, and probably earlier death. The overwhelming majority of patients with mental disorders were not receiving treatment or were being treated in a way that was not recommended. Antipsychotics and antidepressants were not related to the development of metabolic syndrome.</jats:p></jats:sec><jats:sec id="S1092852924000026_sec4" sec-type="conclusions"><jats:title>Conclusions</jats:title><jats:p>The finding that one-third to almost two-thirds of somatic patients also suffered from a mental disorder strongly suggests that psychiatry is the field with the most trans-specialty and interdisciplinary value and application points to the importance of teaching psychiatry and mental health in medical schools and also to the need for more technocratically oriented training of psychiatric residents.</jats:p></jats:sec>enEpidemiologydisabilitymulticomorbiditypremature deathsomatic-mental comorbidity600 - Technology::610 - Medicine & health100 - Philosophy::150 - Psychologyarticle10.48620/882963826957410.1017/s1092852924000026