Klenke, Frank M.Frank M.KlenkeAbdollahi, AmirAmirAbdollahiBischof, MarcMarcBischofGebhard, Martha-MariaMartha-MariaGebhardEwerbeck, VolkerVolkerEwerbeckHuber, Peter EPeter EHuberSckell, AxelAxelSckell2024-10-112024-10-112011https://boris-portal.unibe.ch/handle/20.500.12422/77875Cyclooxygenase-2 (COX-2) inhibitors mediate a systemic antitumor activity via antiangiogenesis and seem to enhance the response of primary tumors to radiation. Radiosensitizing effects of COX-2 inhibition have not been reported for bone metastases. Therefore, the aim of this study was the investigation of the radiosensitizing effects of the selective COX-2 inhibitor celecoxib in secondary bone tumors of a non-small cell lung carcinoma in vivo.enCelecoxib enhances radiation response of secondary bone tumors of a human non-small cell lung cancer via antiangiogenesis in vivoarticle10.48350/74212123453100028671160000710.1007/s00066-010-2116-3