Jost, GéraldineGéraldineJostSchwendener, SybilleSybilleSchwendenerLiassine, NadiaNadiaLiassinePerreten, VincentVincentPerreten0000-0001-5722-94452025-01-082025-01-082021-10-26https://boris-portal.unibe.ch/handle/20.500.12422/201694A hemolytic Macrococcus canis strain (LI021) was isolated for the first time from a human skin infection. The complete genome of LI021 consisting of a 2,216,765-bp circular chromosome was obtained by de novo hybrid assembly of Illumina and Oxford Nanopore technology reads. Strain LI021 belonged to the new sequence type ST75 and was resistant to β-lactam antibiotics due to the presence of a methicillin resistance gene mecB. The mecB gene as well as putative hemolysin genes hlgB and hlgC were located on a novel composite pseudo (Ψ) SCCmec island. These findings show that a methicillin-resistant M. canis may be associated with human infection and indicate that this bacterium should be considered by human diagnostic laboratories.enAntibiotic resistance Dog Human Opportunistic pathogen SCCmec element WGS500 - Science::570 - Life sciences; biology600 - Technology::630 - Agriculturearticle10.48350/1607673471538510.1016/j.meegid.2021.105125