Liew, Sook-LeiSook-LeiLiewZavaliangos-Petropulu, ArtemisArtemisZavaliangos-PetropuluJahanshad, NedaNedaJahanshadLang, Catherine ECatherine ELangHayward, Kathryn SKathryn SHaywardLohse, Keith RKeith RLohseJuliano, Julia MJulia MJulianoAssogna, FrancescaFrancescaAssognaBaugh, Lee ALee ABaughBhattacharya, Anup KAnup KBhattacharyaBigjahan, BavrinaBavrinaBigjahanBorich, Michael RMichael RBorichBoyd, Lara ALara ABoydBrodtmann, AmyAmyBrodtmannBuetefisch, Cathrin MCathrin MBuetefischByblow, Winston DWinston DByblowCassidy, Jessica MJessica MCassidyConforto, Adriana BAdriana BConfortoCraddock, R CameronR CameronCraddockDimyan, Michael AMichael ADimyanDula, Adrienne NAdrienne NDulaErmer, ElsaElsaErmerEtherton, Mark RMark REthertonFercho, Kelene AKelene AFerchoGregory, Chris MChris MGregoryHadidchi, ShahramShahramHadidchiHolguin, Jess AJess AHolguinHwang, Darryl HDarryl HHwangJung, SimonSimonJungKautz, Steven ASteven AKautzKhlif, Mohamed SalahMohamed SalahKhlifKhoshab, NimaNimaKhoshabKim, BokkyuBokkyuKimKim, HosungHosungKimKuceyeski, AmyAmyKuceyeskiLotze, MartinMartinLotzeMacIntosh, Bradley JBradley JMacIntoshMargetis, John LJohn LMargetisMohamed, Feroze BFeroze BMohamedPiras, FabrizioFabrizioPirasRamos-Murguialday, AnderAnderRamos-MurguialdayRichard, GenevièveGenevièveRichardRoberts, PamelaPamelaRobertsRobertson, Andrew DAndrew DRobertsonRondina, Jane MJane MRondinaRost, Natalia SNatalia SRostSanossian, NersesNersesSanossianSchweighofer, NicolasNicolasSchweighoferSeo, Na JinNa JinSeoShiroishi, Mark SMark SShiroishiSoekadar, Surjo RSurjo RSoekadarSpalletta, GianfrancoGianfrancoSpallettaStinear, Cathy MCathy MStinearSuri, AnishaAnishaSuriTang, Wai Kwong WWai Kwong WTangThielman, Gregory TGregory TThielmanVecchio, DanielaDanielaVecchioVillringer, ArnoArnoVillringerWard, Nick SNick SWardWerden, EmilioEmilioWerdenWestlye, Lars TLars TWestlyeWinstein, CaroleeCaroleeWinsteinWittenberg, George FGeorge FWittenbergWong, Kristin AKristin AWongYu, ChunshuiChunshuiYuCramer, Steven CSteven CCramerThompson, Paul MPaul MThompson2024-09-022024-09-022022-01https://boris-portal.unibe.ch/handle/20.500.12422/37772The goal of the Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) Stroke Recovery working group is to understand brain and behavior relationships using well-powered meta- and mega-analytic approaches. ENIGMA Stroke Recovery has data from over 2,100 stroke patients collected across 39 research studies and 10 countries around the world, comprising the largest multisite retrospective stroke data collaboration to date. This article outlines the efforts taken by the ENIGMA Stroke Recovery working group to develop neuroinformatics protocols and methods to manage multisite stroke brain magnetic resonance imaging, behavioral and demographics data. Specifically, the processes for scalable data intake and preprocessing, multisite data harmonization, and large-scale stroke lesion analysis are described, and challenges unique to this type of big data collaboration in stroke research are discussed. Finally, future directions and limitations, as well as recommendations for improved data harmonization through prospective data collection and data management, are provided.enMRI big data lesions neuroinformatics stroke600 - Technology::610 - Medicine & healtharticle10.7892/boris.1477083231033110.1002/hbm.25015