Müller, BornaBornaMüllerDürr, Salome EstherSalome EstherDürr0000-0002-7321-5980Alonso, SilviaSilviaAlonsoHattendorf, JanJanHattendorfLaisse, Cláudio J. M.Cláudio J. M.LaisseParsons, Sven D. C.Sven D. C.Parsonsvan Helden, Paul D.Paul D.van HeldenZinsstag, JakobJakobZinsstag2025-01-082025-01-082013-06https://boris-portal.unibe.ch/handle/20.500.12422/196958We aimed to estimate the global occurrence of zoonotic tuberculosis (TB) caused by Mycobacterium bovis or M. caprae infections in humans by performing a multilingual, systematic review and analysis of relevant scientific literature of the last 2 decades. Although information from many parts of the world was not available, data from 61 countries suggested a low global disease incidence. In regions outside Africa included in this study, overall median proportions of zoonotic TB of ≤1.4% in connection with overall TB incidence rates ≤71/100,000 population/year suggested low incidence rates. For countries of Africa included in the study, we multiplied the observed median proportion of zoonotic TB cases of 2.8% with the continental average overall TB incidence rate of 264/100,000 population/year, which resulted in a crude estimate of 7 zoonotic TB cases/100,000 population/year. These generally low incidence rates notwithstanding, available data indicated substantial consequences of this disease for some population groups and settings.en600 - Technology::630 - Agriculturearticle10.7892/boris.449252373554010.3201/eid1906.120543