Grehn, MelanieMelanieGrehnMandija, StefanoStefanoMandijaMiszczyk, MarcinMarcinMiszczykKrug, DavidDavidKrugTomasik, BartłomiejBartłomiejTomasikStickney, Kristine EKristine EStickneyAlcantara, PinoPinoAlcantaraAlongi, FilippoFilippoAlongiAnselmino, MatteoMatteoAnselminoAranda, Ricardo SalgadoRicardo SalgadoArandaBalgobind, Brian VBrian VBalgobindBoda-Heggemann, JuditJuditBoda-HeggemannBoldt, Leif-HendrikLeif-HendrikBoldtBottoni, NicolaNicolaBottoniCvek, JakubJakubCvekEliçin, OlgunOlgunEliçinDe Ferrari, Gaetano MariaGaetano MariaDe FerrariHassink, Rutger JRutger JHassinkHazelaar, ColienColienHazelaarHindricks, GerhardGerhardHindricksHurkmans, CoenCoenHurkmansIotti, CinziaCinziaIottiJadczyk, TomaszTomaszJadczykJiravsky, OtakarOtakarJiravskyJumeau, RaphaëlRaphaëlJumeauBuus Kristiansen, SteenSteenBuus KristiansenLevis, MarioMarioLevisLópez, Manuel AlgaraManuel AlgaraLópezMartí-Almor, JulioJulioMartí-AlmorMehrhof, FelixFelixMehrhofMøller, Ditte SlothDitte SlothMøllerMolon, GiulioGiulioMolonOuss, AlexandreAlexandreOussPeichl, PetrPetrPeichlPlasek, JiriJiriPlasekPostema, Pieter GPieter GPostemaQuesada, AurelioAurelioQuesadaReichlin, Tobias RomanTobias RomanReichlin0000-0002-7197-8415Rordorf, RobertoRobertoRordorfRudic, BorisBorisRudicSaguner, Ardan MArdan MSagunerTer Bekke, Rachel M ARachel M ATer BekkeTorrecilla, José LópezJosé LópezTorrecillaTroost, Esther G CEsther G CTroostVitolo, VivianaVivianaVitoloAndratschke, NicolausNicolausAndratschkeZeppenfeld, KatjaKatjaZeppenfeldBlamek, SlawomirSlawomirBlamekFast, MartinMartinFastde Panfilis, LudovicaLudovicade PanfilisBlanck, OliverOliverBlanckPruvot, EtienneEtiennePruvotVerhoeff, Joost J CJoost J CVerhoeff2024-10-252024-10-252023-04-15https://boris-portal.unibe.ch/handle/20.500.12422/164829The EU Horizon 2020 Framework-funded Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary (STOPSTORM) consortium has been established as a large research network for investigating STereotactic Arrhythmia Radioablation (STAR) for ventricular tachycardia (VT). The aim is to provide a pooled treatment database to evaluate patterns of practice and outcomes of STAR and finally to harmonize STAR within Europe. The consortium comprises 31 clinical and research institutions. The project is divided into nine work packages (WPs): (i) observational cohort; (ii) standardization and harmonization of target delineation; (iii) harmonized prospective cohort; (iv) quality assurance (QA); (v) analysis and evaluation; (vi, ix) ethics and regulations; and (vii, viii) project coordination and dissemination. To provide a review of current clinical STAR practice in Europe, a comprehensive questionnaire was performed at project start. The STOPSTORM Institutions' experience in VT catheter ablation (83% ≥ 20 ann.) and stereotactic body radiotherapy (59% > 200 ann.) was adequate, and 84 STAR treatments were performed until project launch, while 8/22 centres already recruited VT patients in national clinical trials. The majority currently base their target definition on mapping during VT (96%) and/or pace mapping (75%), reduced voltage areas (63%), or late ventricular potentials (75%) during sinus rhythm. The majority currently apply a single-fraction dose of 25 Gy while planning techniques and dose prescription methods vary greatly. The current clinical STAR practice in the STOPSTORM consortium highlights potential areas of optimization and harmonization for substrate mapping, target delineation, motion management, dosimetry, and QA, which will be addressed in the various WPs.enCardiac arrhythmias Consortium EU Horizon 2020 Stereotactic arrhythmia radioablation Stereotactic body radiotherapy Ventricular tachycardia600 - Technology::610 - Medicine & healtharticle10.48350/1796753687946410.1093/europace/euac238