Moreno, RuiRuiMorenoRhodes, AndrewAndrewRhodesPiquilloud, LiseLisePiquilloudHernandez, GlennGlennHernandezTakala, JukkaJukkaTakalaGershengorn, Hayley BHayley BGershengornTavares, MiguelMiguelTavaresCoopersmith, Craig MCraig MCoopersmithMyatra, Sheila NSheila NMyatraSinger, MervynMervynSingerRezende, EderlonEderlonRezendePrescott, Hallie CHallie CPrescottSoares, MárcioMárcioSoaresTimsit, Jean-FrançoisJean-FrançoisTimsitde Lange, Dylan WDylan Wde LangeJung, ChristianChristianJungDe Waele, Jan JJan JDe WaeleMartin, Greg SGreg SMartinSummers, CharlotteCharlotteSummersAzoulay, ElieElieAzoulayFujii, TomokoTomokoFujiiMcLean, Anthony SAnthony SMcLeanVincent, Jean-LouisJean-LouisVincent2024-10-152024-10-152023-01-13https://boris-portal.unibe.ch/handle/20.500.12422/120521The Sequential Organ Failure Assessment (SOFA) score was developed more than 25 years ago to provide a simple method of assessing and monitoring organ dysfunction in critically ill patients. Changes in clinical practice over the last few decades, with new interventions and a greater focus on non-invasive monitoring systems, mean it is time to update the SOFA score. As a first step in this process, we propose some possible new variables that could be included in a SOFA 2.0. By so doing, we hope to stimulate debate and discussion to move toward a new, properly validated score that will be fit for modern practice.en600 - Technology::610 - Medicine & healtharticle10.48350/1773983663978010.1186/s13054-022-04290-9