Lincke, Joel-BenjaminJoel-BenjaminLinckeMiller, MathiasMathiasMillerEbneter, AndreasAndreasEbneter0000-0001-6666-2558Zinkernagel, Martin SebastianMartin SebastianZinkernagel0000-0003-3447-23592024-10-242024-10-242016-10https://boris-portal.unibe.ch/handle/20.500.12422/146891PURPOSE To assess whether iris-claw intraocular lenses (IOLs) undergo gravitation-dependent changes in position and refraction. SETTING Tertiary referral center, Bern, Switzerland. DESIGN Observational case study. METHODS Patients with a history of pars plana vitrectomy and IOL exchange with implantation of an aphakic iris-claw IOL (Artisan) were included in this study. Objective refraction was obtained with a handheld autorefractometer, and the IOL position was measured by ultrasound biomicroscopy with the patient prone, sitting, and supine. RESULTS Twenty-one eyes of 19 patients with retropupilary IOLs (13) or prepupillary IOLs (8) were included. The mean spherical equivalent (SE) in the sitting position was -0.81 diopter (D) ± 0.95 (SD), and the mean distance from the endothelium to the anterior edge of the IOL was 3.35 ± 0.72 mm. The mean SE in the supine position was -0.61 ± 1.28 D, whereas the mean SE in the prone position was -1.34 ± 1.17 D (P = .0030). The IOL position changed from 3.50 mm in the supine position to 3.06 mm in the prone position (P < .0001). CONCLUSIONS The aphakic iris-claw IOL was subject to significant movement related to gravity. The change in the refractive effect suggests that there is a degree of pseudoaccommodation caused by the forward shift of the aphakic IOL in the face-down position. FINANCIAL DISCLOSURE None of the authors has a financial or proprietary interest in any material or method mentioned.en600 - Technology::610 - Medicine & healtharticle10.7892/boris.910402783960010.1016/j.jcrs.2016.07.033