Debray, Thomas P AThomas P ADebrayMoons, Karel G MKarel G MMoonsvan Valkenhoef, GertGertvan ValkenhoefEfthimiou, OrestisOrestisEfthimiouHummel, NoemiNoemiHummelGroenwold, Rolf H HRolf H HGroenwoldReitsma, Johannes BJohannes BReitsma2024-10-232024-10-232015-08-19https://boris-portal.unibe.ch/handle/20.500.12422/137076Individual participant data (IPD) meta-analysis is an increasingly used approach for synthesizing and investigating treatment effect estimates. Over the past few years, numerous methods for conducting an IPD meta-analysis (IPD-MA) have been proposed, often making different assumptions and modeling choices while addressing a similar research question. We conducted a literature review to provide an overview of methods for performing an IPD-MA using evidence from clinical trials or non-randomized studies when investigating treatment efficacy. With this review, we aim to assist researchers in choosing the appropriate methods and provide recommendations on their implementation when planning and conducting an IPD-MA. © 2015 The Authors. Research Synthesis Methods published by John Wiley & Sons, Ltd.enIPDNRSIRCTcross-designevidence synthesismeta-analysisnon-randomized interventionstudies review600 - Technology::610 - Medicine & health300 - Social sciences, sociology & anthropology::360 - Social problems & social servicesarticle10.7892/boris.746222628781210.1002/jrsm.1160