Jörger, PhilippaPhilippaJörgerNigg, CarinaCarinaNigg0000-0002-0225-1503Žarković, MašaMašaŽarkovićSommer, GritGritSommerKompis, MartinMartinKompisMichel, GiselaGiselaMichel0000-0002-9589-0928Ansari, MarcMarcAnsariWaespe , NicolasNicolasWaespeKuehni, Claudia E.Claudia E.Kuehni2025-04-302025-04-302025-03-27https://boris-portal.unibe.ch/handle/20.500.12422/209466Objectives The International Guideline Harmonization Group recommends childhood cancer survivors (CCS) exposed to ototoxic treatments be aware of the risk of hearing loss. We assessed awareness among adult CCS.Methods We identified adults diagnosed with cancer < 20 years who received ototoxic treatments through the Swiss Childhood Cancer Registry (ChCR) and invited them to the HEAR-study. Participants completed a questionnaire and underwent pure-tone audiometry. Cancer and treatment data were obtained from the ChCR. We used logistic regression to explore factors influencing awareness.Results Of 424 invited, 105 CCS participated (25 %). Fifty-seven percent did not remember receiving information on hearing loss prior to the study. CCS who remembered being informed were more likely diagnosed after 1995 (OR: 4.5, 95 % CI: 1.3-15.4), reported hearing problems (10.9, 2.6-45.1) and other late effects (4.1, 1.3-13.2), and treated with platinum chemotherapy only (10.8, 2.2-53.2) versus cranial radiotherapy only. 44 % of participants presented clinically relevant hearing loss.Conclusions Over half of CCS exposed to ototoxic treatments were unaware of their risk of hearing loss.Practice Implications Educating CCS about potential late effects of ototoxic treatments is important to allow early diagnosis and treatment, especially for those who had cancer longer ago and those exposed to cranial radiation.en600 - Technology::610 - Medicine & health300 - Social sciences, sociology & anthropology::360 - Social problems & social servicesarticle10.48620/876554017954510.1016/j.pec.2025.108764