Frei, AdrianaAdrianaFreiAschenbrenner, Lara MarieLara MarieAschenbrenner0000-0001-5847-0281Cattapan, KatjaKatjaCattapanvon Strauss und Torney, FranziskaFranziskavon Strauss und TorneySedlinskà, Marie-AnnaMarie-AnnaSedlinskàMichaud, LaurentLaurentMichaudSaillant, StéphaneStéphaneSaillantOlbrich, SebastianSebastianOlbrichHoman, StephanieStephanieHomanWerdin, SophiaSophiaWerdinWyss, KasparKasparWyssAdorjan, KristinaKristinaAdorjanWalther, SebastianSebastianWalther0000-0003-4026-3561Gysin-Maillart, Anja CarolynAnja CarolynGysin-Maillart2025-06-032025-06-032025https://boris-portal.unibe.ch/handle/20.500.12422/211450ASSIP flex sustainable suicide prevention: a treatment programme for people who have attempted suicide Background: ASSIP flex is a structured, low-threshold brief therapy for individuals with suicidal behavior. As a flexible treatment ap proach, it can be delivered in inpatient, outpatient, and home settings. This study examines its feasibility, acceptability, and clinical application in routine practice. Method: In an observational pre-post study, 105 patients (53.8% women; M = 38.8 years, SD = 15.2) were interviewed before (t0) and after (t1) the ASSIP flex brief intervention. Sociodemographic characteristics, feasibility aspects, and clinical variables were as sessed. In addition, nine therapists evaluated implementation and acceptability. Results: ASSIP flex was mainly recommended by professionals (57.3%) and showed high acceptability, with its adaptability across different treatment settings cited as a key advantage. Patients demonstrated a significant reduction in suicidal ideation (t104 = 4.5, p < 0.001) and depressive symptoms (t104 = 6.0, p < 0.001), as well as an increase in self-efficacy (t104 = –2.3, p < 0.05). Higher perceived effectiveness of ASSIP flex correlated with lower suicidal ideation (r = –0.28, p < 0.01) and depressive symptoms (r = –0.29, p < 0.01), as well as increased self-efficacy (r = 0.22, p < 0.05). Conclusion: ASSIP flex is a versatile treatment option for individuals with suicidal behavior. The results confirm its potential as a promising addition to existing care structures and its ability to address a critical gap in post-attempt care.deSuicide preventionClinical Follow-UPFeasibilityDemandImplementationAcceptancearticle10.48620/883544033644510.23785/TU.2025.02.006