Heimburg, KatarinaKatarinaHeimburgBlennow Nordström, ErikErikBlennow NordströmDankiewicz, JosefJosefDankiewiczFriberg, HansHansFribergGrejs, Anders MAnders MGrejsHänggi, MatthiasMatthiasHänggi0000-0001-5845-031XKeeble, Thomas RThomas RKeebleKirkegaard, HansHansKirkegaardNielsen, NiklasNiklasNielsenRylander, ChristianChristianRylanderTornberg, Åsa BÅsa BTornbergUllén, SusannSusannUllénWise, Matthew PMatthew PWiseCronberg, TobiasTobiasCronbergLilja, GiselaGiselaLilja2024-11-192024-11-192024-11https://boris-portal.unibe.ch/handle/20.500.12422/188948Aims To describe the level of physical activity 6 months after an out-of-hospital cardiac arrest (OHCA) and to explore potential risk factors of a low level of physical activity.Methods Post-hoc analyses of the international multicentre Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac arrest (TTM2) trial. At 6 months, survivors at 61 sites in Europe, Australia and New Zeeland were invited to a follow-up. The participants answered two questions on self-reported physical activity. Answers were categorized as a low, moderate, or high level of physical activity and further dichotomized into a low versus moderate/high level of physical activity. Potential risk factors for a low level of physical activity were collected and investigated by univariable and multivariable logistic regression.Results At 6 months, 807 of 939 (86%) OHCA survivors answered the two questions of physical activity; 34% reported a low, 44% moderate and 22% high level of physical activity. Obesity (OR = 1.75, 95% CI 1.10-2.77, p = 0.018), mobility problems by EuroQol 5 dimensions 5 levels (OR = 1.73, 95% CI 1.06-2.84, p = 0.029), and cognitive impairment by Symbol Digit Modalities Test (OR = 1.78, 95% CI 1.13-2.82, p = 0.013) were significantly associated with a low level of physical activity in the multivariable analysis.Conclusion One third of the OHCA survivors reported a low level of physical activity. Obesity, mobility problems, and cognitive impairment were associated with a low level of physical activity.Gov Identifier NCT02908308.enCardiac arrestCardiovascular risk factorsCognitive functionPatient-reported outcomePhysical activityPhysical function600 - Technology::610 - Medicine & healtharticle10.48620/763513936879710.1016/j.resuscitation.2024.110407