Ahmad, Suhaib JsSuhaib JsAhmadDegiannis, KonstantinosKonstantinosDegiannisBorucki, JosephJosephBoruckiPouwels, SjaakSjaakPouwelsRawaf, David LaithDavid LaithRawafHead, MarionMarionHeadLi, Chun HeiChun HeiLiArchid, RamiRamiArchidAhmed, Ahmed RAhmed RAhmedLala, AnilAnilLalaRaza, WasifWasifRazaMellor, KatieKatieMellorWichmann, DoerteDoerteWichmannExadaktylos, AristomenisAristomenisExadaktylos2024-10-252024-10-252023-03https://boris-portal.unibe.ch/handle/20.500.12422/164438BACKGROUND Since December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),causative pathogen of coronavirus disease 2019 (COVID-19), has triggered a pandemic with challenges for health care systems around the world. Researchers have studied and published on the subject of SARS-CoV-2 and the disease extensively. What is the significance of articles published, shared and cited in the early stages of such a pandemic? MATERIALS AND METHODS A systematic literature search in a time frame of 12 months and analysis rating using Principle Component Analysis (PCA) and Multiple Factor Analysis (MFA) were performed. RESULTS The 100 most cited COVID-19 articles were identified. The majority of these articles were from China (n = 54), followed by United States of America (USA) (n = 21) and United Kingdom (UK) (n = 8). All articles were published in high-ranked, peer-reviewed journals, with research focusing onthe the diagnosis, transmission and therapy of COVID-19. The level of evidence of the 100 most cited COVID-19 articles on average was low. CONCLUSION In the early stages of a pandemic, new and innovative research can emerge and be highly cited, regardless of the level of evidence.enCOVID-19 Citations ICU care Intensive care SARS-CoV-2600 - Technology::610 - Medicine & healtharticle10.48350/1791683681649110.1016/j.nmni.2023.101094