Luder, GereGereLuderAeberli, DanielDanielAeberliMueller Mebes, ChristineChristineMueller MebesHaupt-Bertschy, BettinaBettinaHaupt-BertschyVerra, Martin LMartin LVerraBaeyens, Jean-PierreJean-PierreBaeyens2024-10-092024-10-092022-03-01https://boris-portal.unibe.ch/handle/20.500.12422/68011OBJECTIVES Generalized joint hypermobility (GJH) has a prevalence in women of 15% to 35%. GJH may lead to impaired movement control, frequent sprains or subluxations and pain, and can be associated with early osteoarthritis or chronic fatigue. Aim of this project was to analyse muscle strength, muscle cross-sectional area (mCSA) and daily function in women with GJH and to analyse correlations between these measurements. METHODS Descriptive cross-sectional study of women with GJH, defined by Beighton score ≥6/9. Assessments included muscle strength, mCSA by peripheral Quantitative Computed Tomography (pQCT), stair climbing, as well as two questionnaires. Spearman's correlations between parameters were calculated. RESULTS 51 women with a mean age of 26.5 years participated, whereof 18 (35%) had a Beighton score of 9/9 and 17 (33%) attained 8/9. Internal correlations between strength measurements were high, whereas pQCT parameters were less correlated. Strength was moderately correlated with mCSA, while correlations with stair climbing and SF-36 were not significant. CONCLUSIONS This study provides insight into the muscle and bone properties of women with GJH. Only slight differences were seen compared to normative values. Correlations between various dimensions were middle or low, indicating the complex relationship between strength, muscle properties and function.enBeighton Score Disability Muscle Cross-Sectional-Area Muscle Strength Stair Climbing600 - Technology::610 - Medicine & healtharticle10.48350/16631435234155