First report of a multidrug-resistant Klebsiella pneumoniae of sequence type 11 causing sepsis in a free-ranging beaver (Castor fiber).

Pilo, PaolaPaolaPiloVogt, DeboraDeboraVogtOriggi, Francesco CFrancesco COriggiEndimiani, AndreaAndreaEndimiani0000-0003-3186-5421Peterson, SusanneSusannePetersonPerreten, VincentVincentPerreten0000-0001-5722-94452025-01-082025-01-082015-04https://boris-portal.unibe.ch/handle/20.500.12422/197694Klebsiella pneumoniae of sequence type (ST) 11 is a hyper-epidemic nosocomial clone spreading worldwide among humans and also emerging in pets. In this report, we describe a clinical case of fatal sepsis due to this multidrug-resistant (MDR) pathogen in a Eurasian beaver. The isolate showed resistance to six different classes of antimicrobials including third generation cephalosporins and fluoroquinolones. This is the first report describing the detection of a MDR K. pneumoniae ST11 in a free-ranging animal. Our finding highlights the potential for environmental dissemination of hyper-epidemic clones of K. pneumoniae and possible spread in wildlife and cause epizootics.en500 - Science::570 - Life sciences; biology600 - Technology::610 - Medicine & healthFirst report of a multidrug-resistant Klebsiella pneumoniae of sequence type 11 causing sepsis in a free-ranging beaver (Castor fiber).article10.7892/boris.688432550475710.1111/1758-2229.12257