# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
Effect of Decompressive Craniectomy on Perihematomal Edema in Patients with Intracerebral Hemorrhage.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.abstract[].value
BACKGROUND

Perihematomal edema contributes to secondary brain injury in the course of intracerebral hemorrhage. The effect of decompressive surgery on perihematomal edema after intracerebral hemorrhage is unknown. This study analyzed the course of PHE in patients who were or were not treated with decompressive craniectomy.

METHODS

More than 100 computed tomography images from our published cohort of 25 patients were evaluated retrospectively at two university hospitals in Switzerland. Computed tomography scans covered the time from admission until day 100. Eleven patients were treated by decompressive craniectomy and 14 were treated conservatively. Absolute edema and hematoma volumes were assessed using 3-dimensional volumetric measurements. Relative edema volumes were calculated based on maximal hematoma volume.

RESULTS

Absolute perihematomal edema increased from 42.9 ml to 125.6 ml (192.8%) after 21 days in the decompressive craniectomy group, versus 50.4 ml to 67.2 ml (33.3%) in the control group (Δ at day 21 = 58.4 ml, p = 0.031). Peak edema developed on days 25 and 35 in patients with decompressive craniectomy and controls respectively, and it took about 60 days for the edema to decline to baseline in both groups. Eight patients (73%) in the decompressive craniectomy group and 6 patients (43%) in the control group had a good outcome (modified Rankin Scale score 0 to 4) at 6 months (P = 0.23).

CONCLUSIONS

Decompressive craniectomy is associated with a significant increase in perihematomal edema compared to patients who have been treated conservatively. Perihematomal edema itself lasts about 60 days if it is not treated, but decompressive craniectomy ameliorates the mass effect exerted by the intracerebral hemorrhage plus the perihematomal edema, as reflected by the reduced midline shift.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
600 - Technology::610 - Medicine & health

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
Effect of Decompressive Craniectomy on Perihematomal Edema in Patients with Intracerebral Hemorrhage.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
The CREp program and the ICE-D production rate calibration database: A fully parameterizable and updated online tool to compute cosmic-ray exposure ages

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.abstract[].value
Over the last decades, cosmogenic exposure dating has permitted major advances in many fields of Earth surface sciences and particularly in paleoglaciology. Yet, exposure age calculation remains a complicated and dense procedure. It requires numerous choices of parameterization and the use of an accurate production rate.
This study describes the CREp program and the ICE-D production rate online database. This system is designed so that the CREp calculator will automatically reflect the current state of this global calibration database production rate, ICE-D. ICE-D will be regularly updated in order to incorporate new calibration data and reflect the current state of the available literature.
CREp is a Octave/Matlab© online code that computes Cosmic Ray Exposure (CRE) ages for 3He and 10Be, available at crep.crpg.cnrs-nancy.fr. A stand-alone version of the CREp code is also released with the present article. Note however that only the online version is connected to the online database ICE-D. The CREp program offers the possibility to calculate ages with two scaling models: i.e. the empirical Lal-Stone time-dependent model (Balco et al., 2008; Lal, 1991; Stone, 2000) with the muon parameters of Braucher et al. (2011), and the Lifton-Sato-Dunai (LSD) theoretical model (Lifton et al., 2014). The default atmosphere model is the ERA-40 database (Uppala et al., 2005), but one may also use the standard atmosphere for comparison (N.O.A.A, 1976) to apply the atmospheric correction. To perform the time-dependent correction, users may import their own geomagnetic database for paleomagnetic corrections or opt for one of the three proposed datasets (Lifton, 2016; Lifton et al., 2014; Muscheler et al., 2005).
For the important choice of the production rate, CREp is linked to a database of production rate calibration data that is part of the ICE-D (Informal Cosmogenic-nuclide Exposure-age Database) project (http://calibration.ice-d.org). This database includes published empirical calibration rate studies that are publicly available at present, comprising those of the CRONUS-Earth and CRONUS-EU projects, as well as studies from other projects. In the present study, the efficacy of the different scaling models has also been evaluated looking at the statistical dispersion of the computed Sea Level High Latitude (SLHL) production rates. Lal/Stone and LSD models have comparable efficacies, and the impact of the tested atmospheric model and the geomagnetic database is also limited.
Users however have several possibilities to select the production rate: 1) using a worldwide mean value, 2) a regionally averaged value (not available in regions with no data), 3) a local unique value, which can be chosen among the existing dataset or imported by the user, or 4) any combination of single or multiple calibration data.
If a global mean is chosen, the 1σ uncertainty arising from the production rate is about 5% for 10Be and 10% for 3He. If a regional production rate is picked, these uncertainties are potentially lower.
CREp is able to calculate a large number of ages in a reasonable time (typically < 30 s for 50 samples). The user may export a summary table of the computed ages and the density probability function associated with each age (in the form of a spreadsheet).

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
500 - Science::550 - Earth sciences & geology

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
The CREp program and the ICE-D production rate calibration database: A fully parameterizable and updated online tool to compute cosmic-ray exposure ages

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
Do executive dysfunction and freezing of gait in Parkinson's disease share the same neuroanatomical correlates?

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.abstract[].value
Current hypotheses postulate a relationship between executive dysfunction and freezing of gait (FOG) in Parkinson's disease (PD). Hitherto, most evidence comes from entirely clinical approaches, while knowledge about this relationship on the morphological level is sparse. The aim of this study was therefore to assess the overlap of gray matter atrophy associated with FOG and executive dysfunction in PD. We included 18 PD patients with FOG and 20 without FOG in our analysis. A voxel-based morphometry approach was used to reveal voxel clusters in the gray matter which were associated with FOG and executive dysfunction as measured by the Frontal Assessment Battery, respectively. Conjunction analysis was applied to detect overlaps of the associated patterns. FOG correlated with different cortical clusters in the frontal and parietal lobes, whereas those associated with the FAB scores were, although widespread, widely confined to the frontal lobe. Conjunction analysis revealed a significant cluster of gray matter loss in the right dorsolateral prefrontal cortex. We could show that the patterns of neurodegeneration associated with FOG and executive dysfunction (as measured by the FAB) share atrophic changes in the same cortical areas. However, there is also a considerable number of cortical areas where neurodegenerative changes are only unique for either sign. Particularly, the involvement of parietal lobe areas seems to be more specific for FOG.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
600 - Technology::610 - Medicine & health

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
Do executive dysfunction and freezing of gait in Parkinson's disease share the same neuroanatomical correlates?

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
Favourable mid-term outcome after heart transplantation for late Fontan failure.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.abstract[].value
OBJECTIVES

Fontan failure (FF) represents a growing and challenging indication for paediatric orthotopic heart transplantation (OHT). The aim of this study was to identify predictors of the best mid-term outcome in OHT after FF.

METHODS

Twenty-year multi-institutional retrospective analysis on OHT for FF.

RESULTS

Between 1991 and 2011, 61 patients, mean age 15.0 ± 9.7 years, underwent OHT for failing atriopulmonary connection (17 patients = 27.8%) or total cavopulmonary connection (44 patients = 72.2%). Modality of FF included arrhythmia (14.8%), complex obstructions in the Fontan circuit (16.4%), protein-losing enteropathy (PLE) (22.9%), impaired ventricular function (31.1%) or a combination of the above (14.8%). The mean time interval between Fontan completion and OHT was 10.7 ± 6.6 years. Early FF occurred in 18%, requiring OHT 0.8 ± 0.5 years after Fontan. The hospital mortality rate was 18.3%, mainly secondary to infection (36.4%) and graft failure (27.3%). The mean follow-up was 66.8 ± 54.2 months. The overall Kaplan-Meier survival estimate was 81.9 ± 1.8% at 1 year, 73 ± 2.7% at 5 years and 56.8 ± 4.3% at 10 years. The Kaplan-Meier 5-year survival estimate was 82.3 ± 5.9% in late FF and 32.7 ± 15.0% in early FF (P = 0.0007). Late FF with poor ventricular function exhibited a 91.5 ± 5.8% 5-year OHT survival. PLE was cured in 77.7% of hospital survivors, but the 5-year Kaplan-Meier survival estimate in PLE was 46.3 ± 14.4 vs 84.3 ± 5.5% in non-PLE (P = 0.0147). Cox proportional hazards identified early FF (P = 0.0005), complex Fontan pathway obstruction (P = 0.0043) and PLE (P = 0.0033) as independent predictors of 5-year mortality.

CONCLUSIONS

OHT is an excellent surgical option for late FF with impaired ventricular function. Protein dispersion improves with OHT, but PLE negatively affects the mid-term OHT outcome, mainly for early infective complications.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.sponsorship[].value
Universitätsklinik für Herz- und Gefässchirurgie

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.relation.ispartof[].value
European journal of cardio-thoracic surgery

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
600 - Technology::610 - Medicine & health

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
Favourable mid-term outcome after heart transplantation for late Fontan failure.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.author.affiliation[].value
Universitätsklinik für Herz- und Gefässchirurgie

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.relation.ispartofbook[].value
Europäische Enzyklopädie zu Philosophie und Wissenschaften

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
200 - Religion::230 - Christianity & Christian theology

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
300 - Social sciences, sociology & anthropology::310 - Statistics

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
Scientific Political Activism – eine Annäherung an das Verhältnis von Wissenschaft und politischem Engagement seit den 1960er Jahren

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.abstract[].value
Wissenschaft und Politik sind zwei Bereiche, deren Verhältnis im 20. Jahrhundert oft im Modus des Normativen gedacht wurde. Seit Max Webers
berühmtem Vortrag Wissenschaft als Beruf (1917) hat sich die Ansicht etabliert, dass Wissenschaftler*innen der Politik keine Handlungsanweisungen erteilen können und Politiker*innen der Wissenschaft keine Vorgaben machen sollen. Diese normative Grenze zwischen Wissenschaft und Politik – und der mit ihr einhergehende Autonomieanspruch der Wissenschaft – ist aber nicht nur historisch spezifisch in die Entwicklungen des 20. Jahrhunderts eingeschrieben und damit verhältnismäßig jung, sie ist seit ihrer Ziehung auch so oft überschritten worden (Shapin 2019), dass ihre Aufrechterhaltung eher die Ausnahme als die Regel zu bilden scheint. Zwar wurde Webers Trennung in der historischen Forschung schon öfters hinterfragt, und es entstanden Perspektiven und Konzepte, die den historischen Verflechtungen von Wissenschaft und Politik Rechnung tragen. Zu nennen sind etwa der Fokus auf die „Verwissenschaftlichung des Sozialen“ und die Rolle von Expert*innen im Zuge der Entstehung und Konsolidierung des Sozialstaates (Raphael 1996), der Vorschlag, Politik und Wissenschaft als „Ressourcen für einander“ zu untersuchen (Ash 2002; 2010) oder Volker Roelckes (2010) Plädoyer für eine historisch-politische Epistemologie, in der die politische Dimension systematisch in die historische Untersuchung der Wissensproduktion integriert wird. Im Fokus standen dabei aber zumeist die Schnittstellen von staatlichem Regieren und wissenschaftlichem Wissen – in Form von staatlicher Forschungsförderung bis hin zur wissenschaftlichen Fundierung von Regierungswissen.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.relation.ispartof[].value
NTM Zeitschrift für Geschichte der Wissenschaften, Technik und Medizin

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
600 - Technology::610 - Medicine & health

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
Scientific Political Activism – eine Annäherung an das Verhältnis von Wissenschaft und politischem Engagement seit den 1960er Jahren

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
HipMatch: An object-oriented cross-platform program for accurate determination of cup orientation using 2D-3D registration of single standard X-ray radiograph and a CT volume

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.sponsorship[].value
Institut für chirurgische Technologien und Biomechanik (ISTB)

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.relation.ispartof[].value
Computer methods and programs in biomedicine

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
HipMatch: An object-oriented cross-platform program for accurate determination of cup orientation using 2D-3D registration of single standard X-ray radiograph and a CT volume

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.author.affiliation[].value
Institut für chirurgische Technologien und Biomechanik (ISTB)

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
300 - Social sciences, sociology & anthropology::340 - Law

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
Clinical, angiographic, IVUS, and OCT predictors for irregular protrusion after coronary stenting.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.abstract[].value
AIMS

Irregular protrusion identified by optical coherence tomography (OCT) immediately following stent implantation has been reported as an independent predictor for adverse cardiac events at one year. However, baseline characteristics for the development of irregular protrusion are unknown. The aim of the study was to identify predictors for irregular protrusion following stent implantation.

METHODS AND RESULTS

A total of 900 lesions in 786 patients who had post-stent OCT imaging were analysed. The patients were divided into two groups: those with (484 lesions, 456 patients) and those without (416 lesions, 330 patients) irregular protrusion. Baseline characteristics (n=786) as well as pre-stent angiogram (n=786), intravascular ultrasound (IVUS; n=31) and OCT (n=159) findings were compared between the two groups. Multivariate analysis showed that patients with irregular protrusion had higher low-density lipoprotein (LDL) cholesterol levels and lesions with greater stent length, greater percent atheroma volume on IVUS, greater lipid content and a higher prevalence of thrombus on OCT before stent implantation.

CONCLUSIONS

Irregular protrusion was found more frequently in patients with higher LDL cholesterol levels. In addition, lesions treated with longer stents, with greater plaque burden, larger lipid content and a higher prevalence of thrombus were identified as predictors for irregular protrusion following stent implantation.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
Clinical, angiographic, IVUS, and OCT predictors for irregular protrusion after coronary stenting.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.cris.virtual.affiliation[].value
Institut für Psychologie - Support IT/Technik

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.person.affiliation[].value
Institut für Psychologie - Support IT/Technik

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
Vulnerability of buildings exposed to dynamic flooding.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.abstract[].value
Repeatedly,  dynamic  flooding  causes  high  loss  in  many  mountain  regions  all over the world. Dynamic flooding is a group of hazard processes includingfluvial sediment transport, debris floods, and debris flows, as well as to some extent flash flood hazards if these are related to mountaincatchments. Regardless of the magnitude and frequency, the consequences of dynamic flooding are strongly connected to the vulnerability of elements at  risk,  such  as people,  buildings  and  infrastructure.  Several  methods  to  assess  physical vulnerability of buildings towards these processesare available. The plethora of methods andapproaches, however, makes a comparison between different case studies challenging. Assessment   methodscan   be   classified inthree   categories:   vulnerability   matrices, vulnerability curves and vulnerability indices. We provide a short review of these methods and discuss theirdominance in the scientific debate onmountain hazard risk managementover the last decade, giving an emphasis to vulnerability curves. Furthermore, challenges in  vulnerability  assessment  including  data  requirements, uncertainties,  and  needs  for improved event documentation are outlined.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.sponsorship[].value
Geographisches Institut der Universität Bern (GIUB)

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.relation.conference[].value
Debris flows: Disasters, risk, forecast, protection. Proceedings of the 6th International Conference

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
Vulnerability of buildings exposed to dynamic flooding.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.author.affiliation[].value
Geographisches Institut der Universität Bern (GIUB)

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
A New Portrait of Indentured Labour: Vietnamese Labour Migration to Malaysia

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
A New Portrait of Indentured Labour: Vietnamese Labour Migration to Malaysia

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
The Swiss Childhood Cancer Registry: rationale, organisation and results for the years 2001-2005

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.contributor.author[].value
Swiss, Paediatric Oncology Group (SPOG) Scientific Committee

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.abstract[].value
QUESTIONS UNDER STUDY: Childhood cancer is a rare but severe disease. Therefore central registration of all cases is essential for surveillance and management. This paper describes the methodology and basic results of the Swiss Childhood Cancer Registry (SCCR). METHODS: The SCCR was established in 1976, originally as a national hospital-based registry of childhood malignancies. All 9 paediatric oncology-haematology clinics in Switzerland provide baseline and follow-up information on all children diagnosed with cancer. These data are registered centrally and diagnoses are coded according to the International Classification of Childhood Cancer. RESULTS: From 2001-2005, 887 cases of childhood cancer in Swiss residents under the age of 15 years were registered in the SCCR. Of these, 281 (31.7%) were leukaemias, 223 (24.0%) were CNS tumours, and 116 (13.1%) were lymphomas. The age-standardised annual incidence per 1 Million person-years (age below 15 years; world standardisation) was 154.0 (95% CI 143.7-164.3; N = 887). The incidence was higher for boys (170.2, 155.0-185.4; N = 501) than for girls (136.9, 123.0-150.8; N = 386). CONCLUSION: The close collaboration between all paediatric oncologists-haematologists in Switzerland and a university department allowed the creation of a national population-based cancer registry with detailed clinical information. The SCCR produces cancer type specific incidence and survival estimates and allows the development of nested research projects on childhood cancer aetiology, management and outcome, both on a national and on an international level.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.sponsorship[].value
Institut für Sozial- und Präventivmedizin (ISPM)

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
600 - Technology::610 - Medicine & health

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
300 - Social sciences, sociology & anthropology::360 - Social problems & social services

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
The Swiss Childhood Cancer Registry: rationale, organisation and results for the years 2001-2005

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.author.affiliation[].value
Institut für Sozial- und Präventivmedizin (ISPM)

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.author.affiliation[].value
Institut für Sozial- und Präventivmedizin (ISPM)

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.author.affiliation[].value
Institut für Sozial- und Präventivmedizin (ISPM)

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.author.affiliation[].value
Institut für Sozial- und Präventivmedizin (ISPM)

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.author.affiliation[].value
Institut für Sozial- und Präventivmedizin (ISPM)

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
Freundschaft und Nähe im spätmittelalterlichen Burgund. Studien zum Spannungsfeld von Emotion und Institution

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.note[].value
Leicht überarb. und aktualisierte Fassung Diss. Techn. Univ. Dresden und Ecole Pratique des Hautes Etudes Paris, 2003/04

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
Freundschaft und Nähe im spätmittelalterlichen Burgund. Studien zum Spannungsfeld von Emotion und Institution

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.sponsorship[].value
Institut für Kunstgeschichte (IKG) - Kunstgeschichte d. Moderne/Gegenwart

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.relation.ispartofbook[].value
The Future Is Unwritten. Position und Politik kunstkritischer Praxis

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.author.affiliation[].value
Institut für Kunstgeschichte (IKG) - Kunstgeschichte d. Moderne/Gegenwart

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
Versorgung eines Patienten mit einer kombiniert zahn- und implantatgetragenen Teleskopprothese - Ein Fallbericht.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.abstract[].value
Durch den Einsatz von Implantaten in Kombination mit zahngetragenen Teleskopprothesen 
kann der Tragekomfort von herausnehmbarem Zahnersatz und somit auch die Zufriedenheit der Patienten mit ungünstiger Pfeilerverteilung erhöht werden. In dem Fallbericht wird beschrieben, wie eine gemischt zahn- und implantatgetragene  Teleskopprothese im Oberkiefer geplant wurde und welche einzelnen Schritte bei der Durchführung erfolgten. Die Besonderheit der gemischt getragenen Hybridprothesen im Vergleich zu rein zahngetragenen Teleskopprothesen lässt sich auf die verschiedenen biologischen Charakteristiken der Pfeiler reduzieren. Aufgrund der bestehenden Verbindung zwischen osseointegrierten Implantaten und natürlichen Zähnen mit physiologischer Zahnbeweglichkeit ist die Passivität der Prothese enorm wichtig. Damit ein möglichst passiver Sitz des Gerüsts garantiert werden kann, wurde dieses im  vorliegenden Fall mit den Sekundärkronen intra oral verklebt. Ein solches Vorgehen ist umso empfehlenswerter, je mehr Implantate in die Prothese einbezogen werden.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.sponsorship[].value
Zahnmedizinische Kliniken, Klinik für Rekonstruktive Zahnmedizin und Gerodontologie

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
600 - Technology::610 - Medicine & health

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
Versorgung eines Patienten mit einer kombiniert zahn- und implantatgetragenen Teleskopprothese - Ein Fallbericht.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.author.affiliation[].value
Zahnmedizinische Kliniken, Klinik für Rekonstruktive Zahnmedizin und Gerodontologie

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.author.affiliation[].value
Zahnmedizinische Kliniken, Klinik für Rekonstruktive Zahnmedizin und Gerodontologie

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
Variability in the measurement of minimum fibrous cap thickness and reproducibility of fibroatheroma classification by optical coherence tomography using manual versus semi-automatic assessment.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.abstract[].value
AIMS

The minimum fibrous cap thickness (FCT) is considered a major criterion of coronary plaque vulnerability according to autopsy studies. We aimed to assess the reproducibility in the measurement of the optical coherence tomography (OCT)-detected minimum FCT and the agreement in the classification of thin-cap fibroatheroma (TCFA), by a software-based semi-automatic method compared with the manual method.

METHODS AND RESULTS

A total of 50 frames with fibroatheromas (FA) were randomly selected from the Integrated Biomarker Imaging Study-4 (IBIS-4). Two experienced OCT analysts independently measured the minimum FCT at two different time points, manually and by three different semi-automatic software-based algorithms, based on the assessment of light intensity along the axial scan line. A TCFA was defined as an FA with minimum FCT <65 μm. The inter- and intra-observer reproducibility of the manual measurement of the minimum FCT was moderate with an intra-class correlation coefficient (ICC) of 0.71 and 0.79, respectively. The corresponding ICCs by either one of the three semi-automatic algorithms were 0.99. When categorising FA according to the minimum FCT based on the manual assessment, the inter- and intra-observer agreement was poor (κ=0.23) and moderate (κ=0.50), respectively. In contrast, the semi-automatic assessment showed perfect agreement for both inter- and intra-observer assessments (κ=0.90-1.00 and 1.00, respectively).

CONCLUSIONS

While semi-automatic assessment of FCT and TCFA classification was associated with excellent reproducibility and agreement, manual measurements were associated with a moderate reproducibility and agreement in the quantification of FCT and classification of TCFA.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
600 - Technology::610 - Medicine & health

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
Variability in the measurement of minimum fibrous cap thickness and reproducibility of fibroatheroma classification by optical coherence tomography using manual versus semi-automatic assessment.

# _embedded.facets[]._embedded.values[].label
300 - Social sciences, sociology & anthropology