# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
Bei virtuellen Nachbarn zu Besuch: Eine Begegnung mit den Musikwelten des Internets

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
Bei virtuellen Nachbarn zu Besuch: Eine Begegnung mit den Musikwelten des Internets

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
Antenatal and postpartum immunological markers levels in women with HIV infection and malnutrition in a low resource setting: A pilot study

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.sponsorship[].value
Universitätsklinik für Viszerale Chirurgie und Medizin - Gastroenterologie

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.sponsorship[].value
Department for BioMedical Research, Forschungsgruppe Gastroenterologie / Mukosale Immunologie

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
600 - Technology::610 - Medicine & health

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
Antenatal and postpartum immunological markers levels in women with HIV infection and malnutrition in a low resource setting: A pilot study

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.author.affiliation[].value
Universitätsklinik für Viszerale Chirurgie und Medizin - Gastroenterologie

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.author.affiliation[].value
Department for BioMedical Research, Forschungsgruppe Gastroenterologie / Mukosale Immunologie

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.author.affiliation[].value
Department for BioMedical Research, Forschungsgruppe Gastroenterologie / Mukosale Immunologie

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.author.affiliation2[].value
Universitätsklinik für Viszerale Chirurgie und Medizin

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.author.affiliation2[].value
Universitätsklinik für Viszerale Chirurgie und Medizin - Gastroenterologie

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Hip MRI in flexion abduction external rotation for assessment of the ischiofemoral interval in patients with hip pain-a feasibility study.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.abstract[].value
OBJECTIVES

To assess the feasibility of flexion-abduction-external rotation (FABER) magnetic resonance imaging (MRI) of the hip to visualize changes in the ischiofemoral interval and ability to provoke foveal excursion over the acetabular rim.

METHODS

IRB-approved retrospective single-center study. Patients underwent non-contrast 1.5-T hip MRI in the neutral and FABER position. Two readers measured the ischiofemoral interval at three levels: proximal/distal intertrochanteric distance and ischiofemoral space. Subgroup analysis was performed for hips with/without high femoral torsion, or quadratus femoris muscle edema (QFME), respectively. A receiver operating curve with calculation of the area under the curve (AUC) for the prediction of QFME was calculated. The presence of foveal excursion in both positions was assessed.

RESULTS

One hundred ten patients (121 hips, mean age 34 ± 11 years, 67 females) were evaluated. FABER-MRI led to narrowing (both p < .001) of the ischiofemoral interval which decreased more at the proximal (mean decrease by 26 ± 7 mm) than at the distal (6 ± 7 mm) intertrochanteric ridge. With high femoral torsion/ QFME, the ischiofemoral interval was significantly narrower at all three measurement locations compared to normal torsion/no QFME (p < .05). Accuracy for predicting QFME was high with an AUC of .89 (95% CI .82-.94) using a threshold of ≤ 7 mm for the proximal intertrochanteric distance. With FABER-MRI foveal excursion was more frequent in hips with QFME (63% vs 25%; p = .021).

CONCLUSION

Hip MRI in the FABER position is feasible, visualizes narrowing of the ischiofemoral interval, and can provoke foveal excursion.

CRITICAL RELEVANCE STATEMENT

FABER MRI may be helpful in diagnosing ischiofemoral impingement and detecting concomitant hip instability by overcoming shortcomings of static MR protocols that do not allow visualization of dynamic changes in the ischiofemoral interval and thus may improve surgical decision making.

KEY POINTS

• FABER MRI enables visualization of narrowing of the ischiofemoral interval proximal to the lesser trochanter. • Proximal intertrochanteric distance of ≤ 7 mm accurately predicts quadratus femoris muscle edema. • Foveal excursion was more frequent in hips with quadratus femoris muscle edema.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject[].value
Femoroacetabular impingement Hip Hip arthroscopy Ischiofemoral impingement Magnetic resonance imaging

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
600 - Technology::610 - Medicine & health

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
Hip MRI in flexion abduction external rotation for assessment of the ischiofemoral interval in patients with hip pain-a feasibility study.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.relation.ispartofbook[].value
Innovationskultur. Von der Wissenschaft zum Produkt

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
A Dose-Response Strategy Reveals Differences between Normal-Weight and Obese Men in Their Metabolic and Inflammatory Responses to a High-Fat Meal.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.abstract[].value
A dose-response strategy may not only allow investigation of the impact of foods and nutrients on human health but may also reveal differences in the response of individuals to food ingestion based on their metabolic health status. In a randomized crossover study, we challenged 19 normal-weight (BMI: 20-25 kg/m(2)) and 18 obese (BMI: >30 kg/m(2)) men with 500, 1000, and 1500 kcal of a high-fat (HF) meal (60.5% energy from fat). Blood was taken at baseline and up to 6 h postprandially and analyzed for a range of metabolic, inflammatory, and hormonal variables, including plasma glucose, lipids, and C-reactive protein and serum insulin, glucagon-like peptide-1, interleukin-6 (IL-6), and endotoxin. Insulin was the only variable that could differentiate the postprandial response of normal-weight and obese participants at each of the 3 caloric doses. A significant response of the inflammatory marker IL-6 was only observed in the obese group after ingestion of the HF meal containing 1500 kcal [net incremental AUC (net iAUC) = 22.9 ± 6.8 pg/mL × 6 h, P = 0.002]. Furthermore, the net iAUC for triglycerides significantly increased from the 1000 to the 1500 kcal meal in the obese group (5.0 ± 0.5 mmol/L × 6 h vs. 6.0 ± 0.5 mmol/L × 6 h, P = 0.015) but not in the normal-weight group (4.3 ± 0.5 mmol/L × 6 h vs. 4.8 ± 0.5 mmol/L × 6 h, P = 0.31). We propose that caloric dose-response studies may contribute to a better understanding of the metabolic impact of food on the human organism. This study was registered at clinicaltrials.gov as NCT01446068.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.sponsorship[].value
Universitätsklinik für Viszerale Chirurgie und Medizin

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
600 - Technology::610 - Medicine & health

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
A Dose-Response Strategy Reveals Differences between Normal-Weight and Obese Men in Their Metabolic and Inflammatory Responses to a High-Fat Meal.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.author.affiliation[].value
Universitätsklinik für Viszerale Chirurgie und Medizin

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
600 - Technology::610 - Medicine & health

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
Rhetoric of Ethnicity and Appeasement During Election Times in Kankan, Guinea

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.sponsorship[].value
Walter Benjamin Kolleg, Interdisziplinäres Forschungs- und Nachwuchsnetzwerk (IFN)

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.relation.conference[].value
10th International Mande Studies Conference

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
300 - Social sciences, sociology & anthropology

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
300 - Social sciences, sociology & anthropology::360 - Social problems & social services

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
300 - Social sciences, sociology & anthropology::380 - Commerce, communications & transportation

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
Rhetoric of Ethnicity and Appeasement During Election Times in Kankan, Guinea

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.author.affiliation[].value
Walter Benjamin Kolleg, Interdisziplinäres Forschungs- und Nachwuchsnetzwerk (IFN)

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
Challenges in proliferative vitreoretinopathy: is biological therapy a solution?

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
600 - Technology::610 - Medicine & health

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
Challenges in proliferative vitreoretinopathy: is biological therapy a solution?

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.author.affiliation2[].value
Department for BioMedical Research (DBMR)

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
Regional impacts of climate change and atmospheric CO2 on future ocean carbon uptake: A multi-model linear feedback analysis

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The increase in atmospheric CO2 over this century depends on the evolution of the oceanic air–sea CO2 uptake, which will be driven by the combined response to rising atmospheric CO2 itself and climate change. Here, the future oceanic CO2 uptake is simulated using an ensemble of coupled climate–carbon cycle models. The models are driven by CO2 emissions from historical data and the Special Report on Emissions Scenarios (SRES) A2 high-emission scenario. A linear feedback analysis successfully separates the regional future (2010–2100) oceanic CO2 uptake into a CO2-induced component, due to rising atmospheric CO2 concentrations, and a climate-induced component, due to global warming. The models capture the observation-based magnitude and distribution of anthropogenic CO2 uptake. The distributions of the climate-induced component are broadly consistent between the models, with reduced CO2 uptake in the subpolar Southern Ocean and the equatorial regions, owing to decreased CO2 solubility; and reduced CO2 uptake in the midlatitudes, owing to decreased CO2 solubility and increased vertical stratification. The magnitude of the climate-induced component is sensitive to local warming in the southern extratropics, to large freshwater fluxes in the extratropical North Atlantic Ocean, and to small changes in the CO2 solubility in the equatorial regions. In key anthropogenic CO2 uptake regions, the climate-induced component offsets the CO2-induced component at a constant proportion up until the end of this century. This amounts to approximately 50% in the northern extratropics and 25% in the southern extratropics and equatorial regions. Consequently, the detection of climate change impacts on anthropogenic CO2 uptake may be difficult without monitoring additional tracers, such as oxygen.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.sponsorship[].value
Physikalisches Institut, Klima- und Umweltphysik (KUP)

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
Regional impacts of climate change and atmospheric CO2 on future ocean carbon uptake: A multi-model linear feedback analysis

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.author.affiliation[].value
Physikalisches Institut, Klima- und Umweltphysik (KUP)

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.author.affiliation[].value
Physikalisches Institut, Klima- und Umweltphysik (KUP)

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
SMS-Kommunikation in der Schweiz: Sprach- und Varietätengebrauch/Text messaging in Switzerland: Use of Languages and varieties/La communication par SMS en Suisse. Utilisation de langues et varietés/La comunicazione mediante SMS in Svizzera: usi di lingue e varietà/La communicaziun per SMS en Svizra: diever da linguas e varietads

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.note[].value
Sonderheft Linguistik online, vol. 48, issue 4

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
SMS-Kommunikation in der Schweiz: Sprach- und Varietätengebrauch/Text messaging in Switzerland: Use of Languages and varieties/La communication par SMS en Suisse. Utilisation de langues et varietés/La comunicazione mediante SMS in Svizzera: usi di lingue e varietà/La communicaziun per SMS en Svizra: diever da linguas e varietads

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.editor.affiliation[].value
Institut für Italienische Sprache und Literatur, Sprachwissenschaft

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
Petrology of basement-dominated terranes: I. Regional metamorphic T–t path from U–Pb monazite and Sm–Nd garnet geochronology (Central Damara orogen, Namibia)

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
500 - Science::550 - Earth sciences & geology

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
Petrology of basement-dominated terranes: I. Regional metamorphic T–t path from U–Pb monazite and Sm–Nd garnet geochronology (Central Damara orogen, Namibia)

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
Offshore-Banking - was eine Schweizer Bank bei Geschäftsbeziehungen mit Personen im Ausland beachten muss

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
300 - Social sciences, sociology & anthropology::340 - Law

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
Offshore-Banking - was eine Schweizer Bank bei Geschäftsbeziehungen mit Personen im Ausland beachten muss

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
Constraints on geological strain rates: Arguments from finite strain states of naturally deformed rocks

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
500 - Science::550 - Earth sciences & geology

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
Constraints on geological strain rates: Arguments from finite strain states of naturally deformed rocks

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.relation.conference[].value
IEEE 19th International Symposium on a World of Wireless, Mobile and Multimedia Networks (WoWMoM)

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
000 - Computer science, knowledge & systems

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
Bewältigung des Klimawandels als Teil der Entwicklungspolitik

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.sponsorship[].value
Centre for Development and Environment (CDE)

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
Bewältigung des Klimawandels als Teil der Entwicklungspolitik

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.author.affiliation[].value
Centre for Development and Environment (CDE)

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.author.affiliation[].value
Centre for Development and Environment (CDE)

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
Cortical remodeling during menopause, rheumatoid arthritis, glucocorticoid and bisphosphonate therapy

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.abstract[].value
Bone mass, bone geometry and its changes are based on trabecular and cortical bone remodeling. Whereas the effects of estrogen loss, rheumatoid arthritis (RA), glucocorticoid (GC) and bisphosphonate (BP) on trabecular bone remodeling have been well described, the effects of these conditions on the cortical bone geometry are less known. The present review will report current knowledge on the effects of RA, GC and BP on cortical bone geometry and its clinical relevance. Estrogen deficiency, RA and systemic GC lead to enhanced endosteal bone resorption. While in estrogen deficiency and under GC therapy endosteal resorption is insufficiently compensated by periosteal apposition, RA is associated with some periosteal bone apposition resulting in a maintained load-bearing capacity and stiffness. In contrast, BP treatment leads to filling of endosteal bone cavities at the epiphysis; however, periosteal apposition at the bone shaft seems to be suppressed. In summary, estrogen loss, RA and GC show similar effects on endosteal bone remodeling with an increase in bone resorption, whereas their effect on periosteal bone remodeling may differ. Despite over 50 years of GC therapy and over 25 years of PB therapy, there is still need for better understanding of the skeletal effects of these drugs as well as of inflammatory disease such as RA on cortical bone remodeling.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
600 - Technology::610 - Medicine & health

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
Cortical remodeling during menopause, rheumatoid arthritis, glucocorticoid and bisphosphonate therapy

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
Antagonistic and synergistic effects of glucocorticoids and IL-7 on CD4+ T cell activation

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.abstract[].value
Glucocorticoids (GCs) are steroidal compounds widely used to treat chronic and acute inflammatory diseases. In particular, GCs at pharmacological doses induce apoptosis of activated and naïve T cells, inhibit their proliferation and block pro-inflammatory cytokine secretion. At physiological concentrations, the effect of these steroids on T cell immunity are not yet fully understood, and various studies reported paradoxical roles exerted by GCs on T cell immunity. Here, we show that GCs surprisingly induce proliferation of activated CD4(+) T cells in the presence of IL-7, a cytokine secreted in the thymus and at mucosal sites. Increased proliferation is dependent on a GC-mediated survival of mitotic cells. Moreover, we observe a downmodulation of Th1 cytokine secretion in cells treated with GCs, an outcome which is not affected by the presence of IL-7. GCs exert thus a positive role in the presence of IL-7 by enhancing proliferation of CD4(+) T cells and simultaneously a negative role by suppressing pro-inflammatory cytokine production.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
Antagonistic and synergistic effects of glucocorticoids and IL-7 on CD4+ T cell activation

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.abstract[].value
Long-term treatment of multiple sclerosis with natalizumab (NTZ) carries the risk of a devastating complication in the form of an encephalopathy caused by a reactivation of a latent John Cunningham virus infection (progressive multifocal leucoencephalopathy, PML). Early diagnosis is associated with considerably better prognosis. Quantitative EEG as an objective, rater-independent technique provides high sensitivity (88) and specificity (82) for the diagnosis of NTZ-PML. Combination of diagnostic modalities addressing static morphological (brain MRI) as well as functional (EEG) pathologic changes may improve risk management programmes.

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject[].value
Eeg John Cunningham virus encephalopathy Multiple sclerosis Natalizumab Pharmacovigilance Screening

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
600 - Technology::610 - Medicine & health

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.name
Magnetic Resonance Imaging Signal Alterations in Paraspinal Muscles in Dogs with Acute Thoracolumbar Intervertebral Disk Extrusion

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.description.sponsorship[].value
Departement für klinische Veterinärmedizin (DKV)

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.subject.ddc[].value
600 - Technology::610 - Medicine & health

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.dc.title[].value
Magnetic Resonance Imaging Signal Alterations in Paraspinal Muscles in Dogs with Acute Thoracolumbar Intervertebral Disk Extrusion

# _embedded.searchResult._embedded.objects[]._embedded.indexableObject.metadata.oairecerif.author.affiliation[].value
Departement für klinische Veterinärmedizin (DKV)

# _embedded.facets[]._embedded.values[].label
300 - Social sciences, sociology & anthropology