Determinants of antibody response to severe acute respiratory syndrome coronavirus 2 mRNA vaccines in people with HIV.
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BORIS DOI
Publisher DOI
PubMed ID
35876706
Description
We identified determinants of SARS-CoV-2 mRNA vaccine antibody response in people with HIV (PWH). Antibody response was higher among PWH less than 60 years, with CD4+ cell count superior to 350 cells/μl and vaccinated with mRNA-1273 by Moderna compared with BNT162b2 by Pfizer-BioNTech. Preinfection with SARS-CoV-2 boosted the antibody response and smokers had an overall lower antibody response. Elderly PWH and those with low CD4+ cell count should be prioritized for booster vaccinations.
Date of Publication
2022-08-01
Publication Type
Article
Subject(s)
Language(s)
en
Contributor(s)
Chammartin, Frédérique | |
Kusejko, Katharina | |
Pasin, Chloé | |
Trkola, Alexandra | |
Briel, Matthias | |
Amico, Patrizia | |
Stoekle, Marcel P | |
Hasse, Barbara | |
Braun, Dominique L | |
Schuurmans, Macé M | |
Müller, Thomas F | |
Tamm, Michael | |
Mueller, Nicolas J | |
Rauch, Andri | |
Koller, Michael T | |
Günthard, Huldrych F | |
Bucher, Heiner C | |
Speich, Benjamin | |
Abela, Irene A |
Additional Credits
Series
AIDS
Publisher
Lippincott Williams & Wilkins
ISSN
0269-9370
Access(Rights)
open.access