Gender-specific elimination of continuous-infusional 5-fluorouracil in patients with gastrointestinal malignancies: results from a prospective population pharmacokinetic study
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BORIS DOI
Date of Publication
2013
Publication Type
Article
Division/Institute
Author
Mueller, F | |
Köberle, D | |
Pfister, B | |
Krähenbühl, St | |
Joerger, M |
Series
Cancer chemotherapy and pharmacology
ISSN or ISBN (if monograph)
0344-5704
Publisher
Springer
Language
English
Publisher DOI
PubMed ID
23139054
Description
This study was initiated to assess the quantitative impact of patient anthropometrics and dihydropyrimidine dehydrogenase (DPYD) mutations on the pharmacokinetics (PK) of 5-fluorouracil (5FU) and to explore limited sampling strategies of 5FU.
File(s)
| File | File Type | Format | Size | License | Publisher/Copright statement | Content | |
|---|---|---|---|---|---|---|---|
| Mueller2013_Article_Gender-specificEliminationOfCo.pdf | text | Adobe PDF | 380.8 KB | published |