Decrease in VEGF expression induces intussusceptive vascular pruning
Options
Date of Publication
2011
Publication Type
Article
Division/Institute
Author
Ehrbar, Martin | |
Reichmuth, Philipp | |
Heinimann, Niklas | |
Escher, Robert | |
Lienemann, Philipp | |
Keshet, Eli | |
Djonov, Valentin Georgiev |
Subject(s)
Series
Arteriosclerosis, thrombosis, and vascular biology
ISSN or ISBN (if monograph)
1079-5642
Publisher
Lippincott Williams & Wilkins
Language
en
Publisher DOI
PubMed ID
21921259
Description
The concept of vascular pruning, the "cuting-off" of vessels, is gaining importance due to expansion of angio-modulating therapies. The proangiogenic effects of vascular endothelial growth factor (VEGF) are broadly described, but the mechanisms of structural alterations by its downregulation are not known.