Interaction of Viral Capsid-Derived Virus-Like Particles (VLPs) with the Innate Immune System.
Options
BORIS DOI
Publisher DOI
PubMed ID
30004398
Description
Virus-like particles (VLPs) derived from viral nucleocapsids are an important class of nanoparticles. The structure, uniformity, stability, and function of these VLPs have attracted scientists in utilizing them as a unique tool in various applications in biomedical fields. Their interaction with the innate immune system is of major importance for the adaptive immune response they induce. The innate immune cells and molecules recognize and interact with VLPs on the basis of two major characteristics: size and surface geometry. This review discusses the interaction of viral capsid-derived VLPs with the innate immune system.
Date of Publication
2018-07-02
Publication Type
Article
Subject(s)
600 - Technology::610 - Medicine & health
Keyword(s)
Toll-like receptor (TLR) adaptive immune system innate immune system virus-like particle (VLP)
Language(s)
en
Additional Credits
Universitätsklinik für Rheumatologie, Immunologie und Allergologie
Series
Vaccines
Publisher
MDPI
ISSN
2076-393X
Access(Rights)
open.access