Provision of critical care for the elderly in Europe: a retrospective comparison of national healthcare frameworks in intensive care units.
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BORIS DOI
Date of Publication
June 3, 2021
Publication Type
Article
Division/Institute
Contributor
Wernly, Bernhard | |
Beil, Michael | |
Bruno, Raphael Romano | |
Binnebössel, Stephan | |
Kelm, Malte | |
Sigal, Sviri | |
van Heerden, Peter Vernon | |
Boumendil, Ariane | |
Artigas, Antonio | |
Cecconi, Maurizio | |
Marsh, Brian | |
Moreno, Rui | |
Oeyen, Sandra | |
Bollen Pinto, Bernardo | |
Szczeklik, Wojciech | |
Leaver, Susannah | |
Walther, Sten Mikael | |
Joannidis, Michael | |
Fjølner, Jesper | |
Zafeiridis, Tilemachos | |
de Lange, Dylan | |
Guidet, Bertrand | |
Flaatten, Hans | |
Jung, Christian |
Subject(s)
Series
BMJ open
ISSN or ISBN (if monograph)
2044-6055
Publisher
BMJ Publishing Group
Language
English
Publisher DOI
PubMed ID
34083342
Uncontrolled Keywords
Description
OBJECTIVES
In Europe, there is a distinction between two different healthcare organisation systems, the tax-based healthcare system (THS) and the social health insurance system (SHI). Our aim was to investigate whether the characteristics, treatment and mortality of older, critically ill patients in the intensive care unit (ICU) differed between THS and SHI.
SETTING
ICUs in 16 European countries.
PARTICIPANTS
In total, 7817 critically ill older (≥80 years) patients were included in this study, 4941 in THS and 2876 in the SHI systems.
PRIMARY AND SECONDARY OUTCOMES MEASURES
We chose generalised estimation equations with robust standard errors to produce population average adjusted OR (aOR). We adjusted for patient-specific variables, health economic data, including gross domestic product (GDP) and human development index (HDI), and treatment strategies.
RESULTS
In SHI systems, there were higher rates of frail patients (Clinical Frailty Scale>4; 46% vs 41%; p<0.001), longer length of ICU stays (90±162 vs 72±134 hours; p<0.001) and increased levels of organ support. The ICU mortality (aOR 1.50, 95% CI 1.09 to 2.06; p=0.01) was consistently higher in the SHI; however, the 30-day mortality (aOR 0.89, 95% CI 0.66 to 1.21; p=0.47) was similar between THS and SHI. In a sensitivity analysis stratifying for the health economic data, the 30-day mortality was higher in SHI, in low GDP per capita (aOR 2.17, 95% CI 1.42 to 3.58) and low HDI (aOR 1.22, 95% CI 1.64 to 2.20) settings.
CONCLUSIONS
The 30-day mortality was similar in both systems. Patients in SHI were older, sicker and frailer at baseline, which could be interpreted as a sign for a more liberal admission policy in SHI. We believe that the observed trend towards ICU excess mortality in SHI results mainly from a more liberal admission policy and an increase in treatment limitations.
TRIAL REGISTRATION NUMBERS
NCT03134807 and NCT03370692.
In Europe, there is a distinction between two different healthcare organisation systems, the tax-based healthcare system (THS) and the social health insurance system (SHI). Our aim was to investigate whether the characteristics, treatment and mortality of older, critically ill patients in the intensive care unit (ICU) differed between THS and SHI.
SETTING
ICUs in 16 European countries.
PARTICIPANTS
In total, 7817 critically ill older (≥80 years) patients were included in this study, 4941 in THS and 2876 in the SHI systems.
PRIMARY AND SECONDARY OUTCOMES MEASURES
We chose generalised estimation equations with robust standard errors to produce population average adjusted OR (aOR). We adjusted for patient-specific variables, health economic data, including gross domestic product (GDP) and human development index (HDI), and treatment strategies.
RESULTS
In SHI systems, there were higher rates of frail patients (Clinical Frailty Scale>4; 46% vs 41%; p<0.001), longer length of ICU stays (90±162 vs 72±134 hours; p<0.001) and increased levels of organ support. The ICU mortality (aOR 1.50, 95% CI 1.09 to 2.06; p=0.01) was consistently higher in the SHI; however, the 30-day mortality (aOR 0.89, 95% CI 0.66 to 1.21; p=0.47) was similar between THS and SHI. In a sensitivity analysis stratifying for the health economic data, the 30-day mortality was higher in SHI, in low GDP per capita (aOR 2.17, 95% CI 1.42 to 3.58) and low HDI (aOR 1.22, 95% CI 1.64 to 2.20) settings.
CONCLUSIONS
The 30-day mortality was similar in both systems. Patients in SHI were older, sicker and frailer at baseline, which could be interpreted as a sign for a more liberal admission policy in SHI. We believe that the observed trend towards ICU excess mortality in SHI results mainly from a more liberal admission policy and an increase in treatment limitations.
TRIAL REGISTRATION NUMBERS
NCT03134807 and NCT03370692.
File(s)
| File | File Type | Format | Size | License | Publisher/Copright statement | Content | |
|---|---|---|---|---|---|---|---|
| 2021_-_Wernly_-_BMJ_Open_-_PMID_34083342.pdf | Adobe PDF | 845.83 KB | published |