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  3. Validation of the 2019 Expert Consensus Algorithm for the Management of Conduction Disturbances After TAVR.
 

Validation of the 2019 Expert Consensus Algorithm for the Management of Conduction Disturbances After TAVR.

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BORIS DOI
10.48350/156336
Date of Publication
May 10, 2021
Publication Type
Article
Division/Institute

Universitätsklinik fü...

Clinical Trials Unit ...

Contributor
Malebranche, Daniel
Bartkowiak, Joanna
Universitätsklinik für Kardiologie
Ryffel, Christoph Philippe
Universitätsklinik für Kardiologie
Bernhard, Benedikt
Universitätsklinik für Kardiologie
Elsmaan, Mamdouh Aly Mohammed
Universitätsklinik für Kardiologie
Nozica, Nikolas
Universitätsklinik für Kardiologie
Okuno, Taishi
Universitätsklinik für Kardiologie
Lanz, Jonas
Universitätsklinik für Kardiologie
Praz, Fabien Daniel
Universitätsklinik für Kardiologie
Stortecky, Stefan
Universitätsklinik für Kardiologie
Räber, Lorenz
Universitätsklinik für Kardiologie
Heg, Dierik Hansorcid-logo
Clinical Trials Unit Bern (CTU)
Roten, Laurentorcid-logo
Universitätsklinik für Kardiologie
Windecker, Stephan
Universitätsklinik für Kardiologie
Pilgrim, Thomas
Universitätsklinik für Kardiologie
Reichlin, Tobias Romanorcid-logo
Universitätsklinik für Kardiologie
Subject(s)

600 - Technology::610...

Series
JACC. Cardiovascular Interventions
ISSN or ISBN (if monograph)
1876-7605
Publisher
Elsevier
Language
English
Publisher DOI
10.1016/j.jcin.2021.03.010
PubMed ID
33958172
Uncontrolled Keywords

ECG algorithm conduct...

Description
OBJECTIVES

The aim of this study was to validate the 2019 consensus algorithm in a large cohort of contemporary transcatheter aortic valve replacement (TAVR) patients.

BACKGROUND

The optimal management of patients with atrioventricular conduction disturbances after TAVR is unknown. Guidance was consolidated in an expert consensus algorithm in 2019.

METHODS

In a retrospective analysis of a prospective registry, patients were classified according to the 2019 consensus algorithm as eligible for early discharge (day 1 or 2 after TAVR), higher risk for high-degree atrioventricular block (HAVB) or complete heart block (CHB) or in need for a permanent pacemaker (PPM). The primary endpoint was the incidence of PPM implantation for HAVB or CHB within 30 days after TAVR. Patients with prior PPM or implantable cardioverter-defibrillator implantation, valve-in-valve procedures, or incomplete electrocardiographic data were excluded.

RESULTS

Among 1,439 patients undergoing TAVR between January 2014 and December 2019, the 2019 consensus algorithm classified 73% as eligible for early discharge, 21% as at higher risk for HAVB or CHB, and 6% as in need of PPM. PPM implantation for HAVB or CHB occurred in 234 patients (16%) within 30 days after TAVR. The incidence of PPM implantation was 2.7% in the early discharge group, 41% in the group with higher risk for HAVB or CHB, and 100% in the PPM group.

CONCLUSIONS

The 2019 consensus algorithm safely identifies patients with no need for PPM implantation. This strategy allows more uniform management of TAVR patients and facilitates early discharge of low-risk patients without prolonged monitoring in 3 of 4 patients. However, the algorithm is less precise in the identification of high-risk patients.
Handle
https://boris-portal.unibe.ch/handle/20.500.12422/42084
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File(s)
FileFile TypeFormatSizeLicensePublisher/Copright statementContent
Malebranche_JACCCardiovascInterv_2021.pdfAdobe PDF1.21 MBpublisherpublished restricted
Malebranche_JACCCardiovascInterv_2021_AAM.pdfAdobe PDF717.06 KBAttribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0)acceptedOpen
Malebranche_JACCCardiovascInterv_2021_supplmat.pdfAdobe PDF264.87 KBAttribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0)supplementalOpen
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