Revolutionizing Stroke Recovery: Unveiling the Promise of Stem Cell Therapy.
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BORIS DOI
Publisher DOI
PubMed ID
38567255
Description
Stem cells, renowned for their unique regenerative capabilities, present significant hope in treating stroke, a major cause of disability globally. This review offers a detailed analysis of stem cell applications in stroke (ischemic and hemorrhagic) recovery. It examines therapies based on autologous (patient-derived), allogeneic (donor-derived), and Granulocyte-Colony Stimulating Factor (G-CSF) based stem cells, focusing on cell types such as Mesenchymal Stem/Stromal Cells (MSCs), Bone Marrow Mononuclear Stem Cells (BMMSCs), and Neural Stem/Progenitor Cells (NSCs). The paper compiles clinical trial data to evaluate their effectiveness and safety and addresses the ethical concerns of these innovative treatments. By explaining the mechanisms of stem cell-induced neurological repair, this review underscores stem cells' potential in revolutionizing stroke rehabilitation and suggests avenues for future research.
Date of Publication
2024
Publication Type
Article
Subject(s)
600 - Technology::610 - Medicine & health
Keyword(s)
allogeneic stem cells transplantation autologous stem cells transplantation brain hemorrhage granulocyte-colony stimulating factor stem cell therapy stroke
Language(s)
en
Contributor(s)
Bargiotas, Panagiotis | |
Hadjigeorgiou, Georgios | |
Panos, Georgios D |
Additional Credits
Universitätsklinik für Neurologie
Series
Drug design, development and therapy
Publisher
Dovepress
ISSN
1177-8881
Access(Rights)
open.access