Lifestyle factors associated with inflammatory bowel disease: data from the Swiss IBD cohort study.
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BORIS DOI
Publisher DOI
PubMed ID
36907848
Description
BACKGROUND
Various environmental risk factors have been associated with the pathogenesis of inflammatory bowel disease. In this study we aimed to identify lifestyle factors that affect the onset of Crohn's disease and ulcerative colitis.
METHODS
2294 patients from the Swiss IBD Cohort Study received a questionnaire regarding physical activity, nutritional habits and status of weight. In addition, a control group was formed comprising patients' childhood friends, who grew up in a similar environment.
RESULTS
Overall, 1111 questionnaires were returned (response rate: 48.4%). Significantly more patients with inflammatory bowel disease reported no regular practice of sport during childhood and beginning of adulthood compared to the control group (p = 0.0001). No association between intake of refined sugar and onset of inflammatory bowel disease was observed. More patients with Crohn's disease compared to ulcerative colitis and controls suffered from overweight during childhood (12.8% vs. 7.7% and 9.7%, respectively; p = 0.027).
CONCLUSIONS
Our study underlines the relevance of environmental factors in the development of inflammatory bowel disease. Our results imply a protective effect of physical activity regarding the onset of inflammatory bowel disease.
Various environmental risk factors have been associated with the pathogenesis of inflammatory bowel disease. In this study we aimed to identify lifestyle factors that affect the onset of Crohn's disease and ulcerative colitis.
METHODS
2294 patients from the Swiss IBD Cohort Study received a questionnaire regarding physical activity, nutritional habits and status of weight. In addition, a control group was formed comprising patients' childhood friends, who grew up in a similar environment.
RESULTS
Overall, 1111 questionnaires were returned (response rate: 48.4%). Significantly more patients with inflammatory bowel disease reported no regular practice of sport during childhood and beginning of adulthood compared to the control group (p = 0.0001). No association between intake of refined sugar and onset of inflammatory bowel disease was observed. More patients with Crohn's disease compared to ulcerative colitis and controls suffered from overweight during childhood (12.8% vs. 7.7% and 9.7%, respectively; p = 0.027).
CONCLUSIONS
Our study underlines the relevance of environmental factors in the development of inflammatory bowel disease. Our results imply a protective effect of physical activity regarding the onset of inflammatory bowel disease.
Date of Publication
2023-03-12
Publication Type
Article
Subject(s)
600 - Technology::610 - Medicine & health
Keyword(s)
Environmental factors Inflammatory bowel disease Nutrition Physical activity Swiss IBD cohort study
Language(s)
en
Contributor(s)
Lautenschlager, Severin A | |
Barry, Mamadou Pathé | |
Rogler, Gerhard | |
Biedermann, Luc | |
Schreiner, Philipp | |
Siebenhüner, Alexander R |
Series
BMC gastroenterology
Publisher
BioMed Central
ISSN
1471-230X
Access(Rights)
open.access