Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases.

BORIS DOI
Date of Publication
February 11, 2016
Publication Type
Article
Division/Institute

Institut für Pharmako...

Contributor
Metcalfe, Dean D
Pawankar, Ruby
Ackerman, Steven J
Akin, Cem
Clayton, Frederic
Falcone, Franco H
Gleich, Gerald J
Irani, Anne-Marie
Johansson, Mats W
Klion, Amy D
Leiferman, Kristin M
Levi-Schaffer, Francesca
Nilsson, Gunnar
Okayama, Yoshimichi
Prussin, Calman
Schroeder, John T
Schwartz, Lawrence B
Walls, Andrew F
Triggiani, Massimo
Subject(s)

600 - Technology::610...

Series
World Allergy Organization journal
ISSN or ISBN (if monograph)
1939-4551
Publisher
Wolters Kluwer Health Lippincott Williams & Wilkins
Language
English
Publisher DOI
PubMed ID
26904159
Description
Biomarkers of disease activity have come into wide use in the study of mechanisms of human disease and in clinical medicine to both diagnose and predict disease course; as well as to monitor response to therapeutic intervention. Here we review biomarkers of the involvement of mast cells, basophils, and eosinophils in human allergic inflammation. Included are surface markers of cell activation as well as specific products of these inflammatory cells that implicate specific cell types in the inflammatory process and are of possible value in clinical research as well as within decisions made in the practice of allergy-immunology.
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