Rituximab as a treatment option for refractory endogenous anterior uveitis
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BORIS DOI
Date of Publication
2007
Publication Type
Article
Division/Institute
Contributor
Heinz, Carsten | |
Specker, Christof | |
Heiligenhaus, Arnd |
Subject(s)
Series
Ophthalmic research
ISSN or ISBN (if monograph)
0030-3747
Publisher
Karger
Language
English
Publisher DOI
PubMed ID
17534119
Description
BACKGROUND
To report on anti-CD20 antibody therapy in a patient with uveitis refractive to immunosuppression therapy.
METHODS
Case report with ophthalmoscopic, optical coherence tomography and fluorescein-angiographic findings.
RESULTS
A 49-year-old woman was suffering from bilateral, noninfectious chronic anterior uveitis refractive to corticosteroids and immunosuppressive drugs. Bilateral visual acuity was 20/100 due to cataract and cystoid macular edema (CME). After treatment with rituximab, vision and CME improved, and uveitis was stable until the final visit (follow-up at 12 months).
CONCLUSION
The case report suggests that rituximab may be helpful for selected patients with chronic anterior uveitis refractive to corticosteroids and immunosuppressive medication.
To report on anti-CD20 antibody therapy in a patient with uveitis refractive to immunosuppression therapy.
METHODS
Case report with ophthalmoscopic, optical coherence tomography and fluorescein-angiographic findings.
RESULTS
A 49-year-old woman was suffering from bilateral, noninfectious chronic anterior uveitis refractive to corticosteroids and immunosuppressive drugs. Bilateral visual acuity was 20/100 due to cataract and cystoid macular edema (CME). After treatment with rituximab, vision and CME improved, and uveitis was stable until the final visit (follow-up at 12 months).
CONCLUSION
The case report suggests that rituximab may be helpful for selected patients with chronic anterior uveitis refractive to corticosteroids and immunosuppressive medication.
File(s)
| File | File Type | Format | Size | License | Publisher/Copright statement | Content | |
|---|---|---|---|---|---|---|---|
| 103239.pdf | text | Adobe PDF | 102.3 KB | published |