Publication:
A 4-year study on clinical characteristics of children hospitalized with rotavirus gastroenteritis

cris.virtualsource.author-orcid7f363741-54c1-4ef6-9891-28361795f5d1
datacite.rightsopen.access
dc.contributor.authorWildi-Runge, Stefanie
dc.contributor.authorAllemann, Sabin
dc.contributor.authorSchaad, Urs B
dc.contributor.authorHeininger, Ulrich
dc.date.accessioned2024-10-14T10:16:33Z
dc.date.available2024-10-14T10:16:33Z
dc.date.issued2009
dc.description.abstractRotavirus (RV) is a frequent cause of severe gastroenteritis (GE) in children. With the licensure of new RV vaccines, data on the burden of disease are important regarding immunization strategies. We reviewed the medical records of children hospitalized with RV infection in our institution between July 2002 and March 2006. Relevant data were extracted in a standardized fashion from records of hospitalized children with a positive RV antigen test in a stool sample. Severity of disease was graded by the 20-point Vesikari score. Population data were obtained from the Federal Office of Statistics. Six hundred eighty-six RVGE were identified and records of 608 hospitalizations (in 607 children) were available. In 539 (89%) cases, RVGE was the primary reason for hospitalization and 69 (11%) were nosocomial infections; yearly peaks occurred between February and May. Cumulative incidence of RVGE was 26.7/1,000 children <3 years of age. Median age of 539 children (55.6% male) with primary RVGE was 1.4 years and median stay in the hospital for both community acquired and nosocomial RVGE was 4 days (interquartile range 3-5). Thirtypercent and 94% of RV hospitalizations were in children <1 and <3 years of age, respectively. Mean Vesikari score was 15 (range 6-20; 96% >11). Intravenous fluids were administered in 378 (70%) patients, 130 (24%) patients were rehydrated via nasogastral tube, and 31 (5.7%) received rehydration by mouth. RVGE causes a substantial burden in children with an estimated risk for hospitalization due to RVGE of one in 37 children <3 years of age.
dc.description.numberOfPages6
dc.description.sponsorshipUniversitätspoliklinik für Endokrinologie, Diabetologie und Klinische Ernährung
dc.identifier.doi10.48350/37207
dc.identifier.isi000269912000008
dc.identifier.pmid19205732
dc.identifier.publisherDOI10.1007/s00431-009-0934-z
dc.identifier.urihttps://boris-portal.unibe.ch/handle/20.500.12422/110431
dc.language.isoen
dc.publisherSpringer
dc.publisher.placeBerlin
dc.relation.ispartofEuropean journal of pediatrics
dc.relation.issn0340-6199
dc.relation.organizationDCD5A442C012E17DE0405C82790C4DE2
dc.titleA 4-year study on clinical characteristics of children hospitalized with rotavirus gastroenteritis
dc.typearticle
dspace.entity.typePublication
dspace.file.typetext
oaire.citation.endPage8
oaire.citation.issue11
oaire.citation.startPage1343
oaire.citation.volume168
oairecerif.author.affiliationUniversitätspoliklinik für Endokrinologie, Diabetologie und Klinische Ernährung
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unibe.date.licenseChanged2022-05-03 12:36:55
unibe.description.ispublishedpub
unibe.eprints.legacyId37207
unibe.journal.abbrevTitleEUR J PEDIATR
unibe.refereedtrue
unibe.subtype.articlejournal

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