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  3. Impact of geography and surgical approach on recurrence in global pilonidal sinus disease.

Impact of geography and surgical approach on recurrence in global pilonidal sinus disease.

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DOI
10.7892/boris.134432
Publisher DOI
10.1038/s41598-019-51159-z
PubMed ID
31641150
Abstract
Pilonidal sinus disease (PSD) is increasing globally. A recent meta-analysis and merged-data analysis showed that recurrence rates in PSD depend essentially on follow-up time and specific surgical procedures. However, the global distribution of surgical approaches and respective recurrence rates have never been studied in PSD. We aimed at studying the impact of geographic distribution of surgical approaches to treat PSD and subsequent geography-specific recurrence rates. We searched relevant databases as described previously. Recurrence rates were then associated with reported follow-up times and geographic origin. We simulated individual patients to enable analogy across data. Globally, recurrence rates range from 0.3% for Limberg/Dufourmentel approaches (95% CI 0.2-0.4) and flaps (95% CI 0.1-0.5) and up to 6.3% for incision (95% CI 3.2-9.3) at 12 months. Recurrence rates range from 0.3% for Karydakis/Bascom approaches (95% CI 0.0-0.8) up to 67.2% for incision (95% CI 7.5-100) in the USA, and 0.0% for primary asymmetric closure in Germany (95% CI 0.0-0.0). Our analysis shows that recurrence rates in PSD not only depend on therapeutic approaches and follow-up time but also on geography. Primary asymmetric closure and various flap techniques remain superior regardless of the geographical region. Some approaches have extraordinarily good outcomes in specific countries.
Date Issued
2019-10-22
Publication Type
Article
Subject(s)
600 Technology > 610 Medicine & health
Language(s)
en
Author(s)
Doll, Dietrich
Orlik, Andriu
Maier, Katharina
Kauf, Peter
Schmid, Marco
Diekmann, Maja
Vogt, Andreas  
Universitätsklinik für Anästhesiologie und Schmerztherapie  
Stauffer, Verena K
Lüdi, Markus  
Universitätsklinik für Anästhesiologie und Schmerztherapie  
Additional Credits
Universitätsklinik für Anästhesiologie und Schmerztherapie  
Journal
Scientific reports
Publisher
Springer Nature
ISSN
2045-2322
Access(Rights)
open.access
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