Mechanisms of aminoglycoside ototoxicity and targets of hair cell protection.
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BORIS DOI
Date of Publication
2011
Publication Type
Article
Division/Institute
Contributor
Subject(s)
Series
International journal of otolaryngology
ISSN or ISBN (if monograph)
1687-921X
Publisher
Hindawi
Language
English
Publisher DOI
PubMed ID
22121370
Description
Aminoglycosides are commonly prescribed antibiotics with deleterious side effects to the inner ear. Due to their popular application as a result of their potent antimicrobial activities, many efforts have been undertaken to prevent aminoglycoside ototoxicity. Over the years, understanding of the antimicrobial as well as ototoxic mechanisms of aminoglycosides has increased. These mechanisms are reviewed in regard to established and potential future targets of hair cell protection.
File(s)
| File | File Type | Format | Size | License | Publisher/Copright statement | Content | |
|---|---|---|---|---|---|---|---|
| 937861.pdf | text | Adobe PDF | 1.56 MB | Attribution (CC BY 4.0) | published |