Publication:
Prevention, diagnosis and treatment of venous thromboembolism in patients with COVID-19: CHEST Guideline and Expert Panel Report.

cris.virtualsource.author-orcid3e6ea3f7-244a-46bb-9b26-003c5df11d76
datacite.rightsopen.access
dc.contributor.authorMoores, Lisa K
dc.contributor.authorTritschler, Tobias
dc.contributor.authorBrosnahan, Shari
dc.contributor.authorCarrier, Marc
dc.contributor.authorCollen, Jacob F
dc.contributor.authorDoerschug, Kevin
dc.contributor.authorHolley, Aaron B
dc.contributor.authorJimenez, David
dc.contributor.authorLeGal, Gregoire
dc.contributor.authorRali, Parth
dc.contributor.authorWells, Philip
dc.date.accessioned2024-09-02T15:58:12Z
dc.date.available2024-09-02T15:58:12Z
dc.date.issued2020-09
dc.description.abstractBACKGROUND Emerging evidence shows that severe COVID-19 can be complicated by a significant coagulopathy, that likely manifests in the form of both microthrombosis and venous thromboembolism (VTE). This recognition has led to the urgent need for practical guidance regarding prevention, diagnosis, and treatment of VTE. METHODS A group of approved panelists developed key clinical questions by using the PICO (population, intervention, comparator, and outcome) format that addressed urgent clinical questions regarding the prevention, diagnosis and treatment of venous thromboembolism in patients with COVID-19. MEDLINE (via PubMed or Ovid), Embase and Cochrane Controlled Register of Trials were systematically searched for relevant literature and references were screened for inclusion. Validated evaluation tools were used to grade the level of evidence to support each recommendation. When evidence did not exist, guidance was developed based on consensus using the modified Delphi process. RESULTS The systematic review and critical analysis of the literature based on13 PICO questions resulted in 22 statements. Very little evidence exists in the COVID-19 population. The panel thus used expert consensus and existing evidence-based guidelines to craft the guidance statements. CONCLUSIONS The evidence on the optimal strategies to prevent, diagnose, and treat venous thromboembolism in patients with COVID-19 is sparse, but rapidly evolving.
dc.description.numberOfPages21
dc.description.sponsorshipClinic of General Internal Medicine
dc.identifier.doi10.7892/boris.144558
dc.identifier.pmid32502594
dc.identifier.publisherDOI10.1016/j.chest.2020.05.559
dc.identifier.urihttps://boris-portal.unibe.ch/handle/20.500.12422/36175
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofChest
dc.relation.issn1931-3543
dc.relation.organizationClinic of General Internal Medicine
dc.subjectCOVID-19 DIC deep vein thrombosis hypercoagulability pulmonary embolism venous thromboembolism
dc.titlePrevention, diagnosis and treatment of venous thromboembolism in patients with COVID-19: CHEST Guideline and Expert Panel Report.
dc.typearticle
dspace.entity.typePublication
oaire.citation.endPage1163
oaire.citation.issue3
oaire.citation.startPage1143
oaire.citation.volume158
oairecerif.author.affiliationClinic of General Internal Medicine
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unibe.date.embargoChanged2021-06-03 00:30:02
unibe.date.licenseChanged2020-06-10 14:17:26
unibe.description.ispublishedpub
unibe.eprints.legacyId144558
unibe.refereedtrue
unibe.subtype.articlereview

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