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  3. Telomerase-specific GV1001 peptide vaccination fails to induce objective tumor response in patients with cutaneous T cell lymphoma

Telomerase-specific GV1001 peptide vaccination fails to induce objective tumor response in patients with cutaneous T cell lymphoma

Details
Publisher DOI
10.1016/j.jdermsci.2011.02.001
PubMed ID
21377838
Abstract
There is currently no curative therapy for cutaneous T cell lymphoma (CTCL). New therapies are therefore needed. Telomerase, the enzyme that allows for unrestricted cell divisions of cancer cells, is a promising target for cancer therapy. The telomerase-specific peptide vaccination GV1001 has shown promising results in previous studies. Since telomerase is expressed in malignant cells of CTCL, GV1001 vaccination in CTCL is a promising new therapeutic approach.
Date Issued
2011
Publication Type
Article
Language(s)
en
Author(s)
Schlapbach, Christoph  
Universitätsklinik für Dermatologie  
Yerly, Daniel  
Universitätsklinik für Rheumatologie, klinische Immunologie und Allergologie  
Daubner, Barbara
Yawalkar, Nikhil  
Universitätsklinik für Dermatologie  
Hunger, Robert  
Universitätsklinik für Dermatologie  
Additional Credits
Universitätsklinik für Dermatologie  
Universitätsklinik für Rheumatologie, klinische Immunologie und Allergologie  
Journal
Journal of dermatological science
Publisher
Elsevier
ISSN
0923-1811
Access(Rights)
metadata.only
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