Malignant Peripheral Nerve Sheath Tumour in a Seba's Short-Tailed Bat (Carollia perspicillata).
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Date of Publication
April 2021
Publication Type
Article
Division/Institute
Contributor
Fasel, Nicolas J | |
Rüegg-van den Broek, Peggy | |
Series
Journal of comparative pathology
ISSN or ISBN (if monograph)
0021-9975
Publisher
Elsevier
Language
English
Publisher DOI
PubMed ID
33894882
Uncontrolled Keywords
BORIS DOI
Description
There are few reports of tumours in bats, despite the fact that members of the Chiroptera order include 22.4% of all currently known mammal species. We now describe a case of malignant peripheral nerve sheath tumour (MPNST) in an adult female Seba's short-tailed bat (Carollia perspicillata) from a private zoo in Switzerland. The macroscopical and histological findings indicated that the MPNST originated from a dorsal spinal nerve root sheath in the lumbar region and metastasized to the spleen. Immunohistochemical labelling for glial fibrillary acid protein, S100 protein, neuron specific enolase and synaptophysin was negative. The cytoplasm of a few neoplastic cells labelled for smooth muscle actin and desmin. To our knowledge, this is the first report of a PNST in a member of the Chiroptera order.