Three-dimensional changes in mandibular jaw cysts following decompression surgery: a retrospective cohort study.
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BORIS DOI
Publisher DOI
PubMed ID
41588406
Description
Background
This retrospective cohort study primarily assessed three-dimensional changes in mandibular jaw cysts over time following decompression surgery. Secondary aims included evaluating factors potentially affecting the monthly reduction rates and assessing intra- and interexaminer reliability in the measurements.Methods
Patients who underwent decompression therapy for mandibular cysts and histopathological diagnosis were included. Cone-beam computed tomography (CBCT) scans obtained before decompression surgery (baseline CBCT) and prior to enucleation surgery (follow-up CBCT) were analyzed using a specialized 3D software to measure cyst dimensions based on preview and final lesion outlines by two examiners. Patient demographics, cyst types, localization, and cortical bone perforation were recorded and evaluated for their influence on dimensional change rates.Results
Forty patients (15 females and 25 males) with a median age of 47 years (range: 11 to 76 years) and treated with decompression of radicular (n = 10), dentigerous (n = 14), botryoid (n = 1), or odontogenic keratocysts (n = 15) were analyzed. The lesions were predominantly located in the posterior mandible (n = 32) and exhibited single (n = 14), multiple (n = 17), or no cortical bone perforations (n = 9). Mean lesion volumes decreased from baseline (3764 mm³) to follow-up (1413 mm³, p < 0.0001), corresponding to an average monthly volumetric reduction rate of -5.2%, without significant differences between the cyst types. Female and younger patients showed higher reduction rates (p ≤ 0.04), whilst localization and cortical bone perforation did not significantly influence the dimensional changes. Both inter- and intraexaminer reliability of measurements were high (intraclass correlation coefficients > 95%).Conclusions
Decompression surgery is an effective first-stage treatment to reduce the dimensions of large mandibular odontogenic cysts. Within a range of limited clinical relevance, patient-related factors such as sex and age may influence dimensional changes, whereas lesion-specific characteristics did not. Cyst measurements on CBCT were consistent across observers, indicating good reproducibility.
This retrospective cohort study primarily assessed three-dimensional changes in mandibular jaw cysts over time following decompression surgery. Secondary aims included evaluating factors potentially affecting the monthly reduction rates and assessing intra- and interexaminer reliability in the measurements.Methods
Patients who underwent decompression therapy for mandibular cysts and histopathological diagnosis were included. Cone-beam computed tomography (CBCT) scans obtained before decompression surgery (baseline CBCT) and prior to enucleation surgery (follow-up CBCT) were analyzed using a specialized 3D software to measure cyst dimensions based on preview and final lesion outlines by two examiners. Patient demographics, cyst types, localization, and cortical bone perforation were recorded and evaluated for their influence on dimensional change rates.Results
Forty patients (15 females and 25 males) with a median age of 47 years (range: 11 to 76 years) and treated with decompression of radicular (n = 10), dentigerous (n = 14), botryoid (n = 1), or odontogenic keratocysts (n = 15) were analyzed. The lesions were predominantly located in the posterior mandible (n = 32) and exhibited single (n = 14), multiple (n = 17), or no cortical bone perforations (n = 9). Mean lesion volumes decreased from baseline (3764 mm³) to follow-up (1413 mm³, p < 0.0001), corresponding to an average monthly volumetric reduction rate of -5.2%, without significant differences between the cyst types. Female and younger patients showed higher reduction rates (p ≤ 0.04), whilst localization and cortical bone perforation did not significantly influence the dimensional changes. Both inter- and intraexaminer reliability of measurements were high (intraclass correlation coefficients > 95%).Conclusions
Decompression surgery is an effective first-stage treatment to reduce the dimensions of large mandibular odontogenic cysts. Within a range of limited clinical relevance, patient-related factors such as sex and age may influence dimensional changes, whereas lesion-specific characteristics did not. Cyst measurements on CBCT were consistent across observers, indicating good reproducibility.
Date of Publication
2026-01-27
Publication Type
Article
Subject(s)
Keyword(s)
Bone Remodeling
•
Cone-Beam Computed Tomography
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Decompression
•
Dentigerous cyst
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Jaw cyst
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Odontogenic Keratocyst
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Radicular Cyst
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Surgical
Language(s)
en
Contributor(s)
Schmidt, Valerie |
Series
BMC Oral Health
Publisher
BioMed Central
ISSN
1472-6831
Access(Rights)
open.access