Publication:
Older Candidates for Subthalamic Deep Brain Stimulation in Parkinson's Disease Have a Higher Incidence of Psychiatric Serious Adverse Events.

Simple item page
cris.virtualsource.author-orcid346186a4-a537-4773-8e5e-689017a507e1
datacite.rightsopen.access
dc.contributor.authorCozac, Vitalii V
dc.contributor.authorEhrensperger, Michael M
dc.contributor.authorGschwandtner, Ute
dc.contributor.authorHatz, Florian
dc.contributor.authorMeyer, Antonia
dc.contributor.authorMonsch, Andreas U
dc.contributor.authorSchüpbach, Michael
dc.contributor.authorTaub, Ethan
dc.contributor.authorFuhr, Peter
dc.date.accessioned2024-10-24T18:33:37Z
dc.date.available2024-10-24T18:33:37Z
dc.date.issued2016
dc.description.abstractOBJECTIVE To investigate the incidence of serious adverse events (SAE) of subthalamic deep brain stimulation (STN-DBS) in elderly patients with Parkinson's disease (PD). METHODS We investigated a group of 26 patients with PD who underwent STN-DBS at mean age 63.2 ± 3.3 years. The operated patients from the EARLYSTIM study (mean age 52.9 ± 6.6) were used as a comparison group. Incidences of SAE were compared between these groups. RESULTS A higher incidence of psychosis and hallucinations was found in these elderly patients compared to the younger patients in the EARLYSTIM study (p < 0.01). CONCLUSIONS The higher incidence of STN-DBS-related psychiatric complications underscores the need for comprehensive psychiatric pre- and postoperative assessment in older DBS candidates. However, these psychiatric SAE were transient, and the benefits of DBS clearly outweighed its adverse effects.
dc.description.sponsorshipUniversitätsklinik für Neurologie
dc.identifier.doi10.7892/boris.90719
dc.identifier.pmid27375478
dc.identifier.publisherDOI10.3389/fnagi.2016.00132
dc.identifier.urihttps://boris-portal.unibe.ch/handle/20.500.12422/146666
dc.language.isoen
dc.publisherFrontiers Research Foundation
dc.relation.ispartofFrontiers in aging neuroscience
dc.relation.issn1663-4365
dc.relation.organizationDCD5A442C22EE17DE0405C82790C4DE2
dc.relation.organizationDCD5A442BAE0E17DE0405C82790C4DE2
dc.subjectParkinson's disease (PD)
dc.subjectadverse events
dc.subjectage factors
dc.subjectdeep brain stimulation (DBS)
dc.subjectpsychosis
dc.subject.ddc600 - Technology::610 - Medicine & health
dc.titleOlder Candidates for Subthalamic Deep Brain Stimulation in Parkinson's Disease Have a Higher Incidence of Psychiatric Serious Adverse Events.
dc.typearticle
dspace.entity.typePublication
dspace.file.typetext
oaire.citation.issue132
oaire.citation.startPage132
oaire.citation.volume8
oairecerif.author.affiliationUniversitätsklinik für Neurologie
oairecerif.author.affiliation2Departement Klinische Forschung, Forschungsgruppe Neurologie
unibe.contributor.rolecreator
unibe.contributor.rolecreator
unibe.contributor.rolecreator
unibe.contributor.rolecreator
unibe.contributor.rolecreator
unibe.contributor.rolecreator
unibe.contributor.rolecreator
unibe.contributor.rolecreator
unibe.contributor.rolecreator
unibe.description.ispublishedpub
unibe.eprints.legacyId90719
unibe.refereedtrue
unibe.subtype.articlejournal

Files

Original bundle
Now showing 1 - 1 of 1
Name:
fnagi-08-00132.pdf
Size:
181.71 KB
Format:
Adobe Portable Document Format
File Type:
text
License:
https://creativecommons.org/licenses/by/4.0
Content:
published
Download

Collections

Publications