Cerebral networks linked to the event-related potential P300
Publisher DOI
PubMed ID
12904980
Abstract
P300 is an event-related potential that is elicited by an oddball paradigm. In several neuropsychiatric diseases, differences in latencies and amplitude compared to healthy subjects have been reported. Because of its clinical significance, several investigations have tried to elucidate the intracranial origins of the P300 component. In the present study we could demonstrate a network of P300 generators. Investigated were 15 healthy subjects with an acoustical oddball paradigm within a fMRI block design, which enabled us to exclude attention or acoustical processing effects. The inferior and middle frontal, superior temporal, lower parietal cortex, the insula and the anterior cingulum were significantly activated symmetrical in both hemispheres.
Date Issued
2003
Publication Type
Article
Language(s)
en
Author(s)
Horn, H | |
Syed, N | |
Lanfermann, H | |
Maurer, K |
Journal
European archives of psychiatry and clinical neuroscience
Publisher
Steinkopff-Verlag
ISSN
0940-1334
ISBN
12904980
Access(Rights)
open.access