Publication:
Individual and population level effects of partner notification for Chlamydia trachomatis

cris.virtual.author-orcid0000-0002-5230-6760
cris.virtual.author-orcid0000-0003-4817-8986
cris.virtualsource.author-orcid6c0e9ae6-71dc-487a-bfe2-5908d1078b9a
cris.virtualsource.author-orcidc8e4151e-e7b6-4f93-a669-2b2bbf48f719
cris.virtualsource.author-orcidf87849aa-f35d-497b-969f-08804459dc74
cris.virtualsource.author-orcidbb5e3f47-d3b5-4015-aac8-1c096b001132
datacite.rightsopen.access
dc.contributor.authorAlthaus, Christian
dc.contributor.authorMin, Johanna
dc.contributor.authorHerzog, Sereina
dc.contributor.authorRoellin, Adrian
dc.contributor.authorLow, Nicola
dc.date.accessioned2024-10-11T13:29:45Z
dc.date.available2024-10-11T13:29:45Z
dc.date.issued2012
dc.description.abstractPartner notification (PN or contact tracing) is an important aspect of treating bacterial sexually transmitted infections (STIs), such as Chlamydia trachomatis. It facilitates the identification of new infected cases that can be treated through individual case management. PN also acts indirectly by limiting onward transmission in the general population. However, the impact of PN, both at the level of individuals and the population, remains unclear. Since it is difficult to study the effects of PN empirically, mathematical and computational models are useful tools for investigating its potential as a public health intervention. To this end, we developed an individual-based modeling framework called Rstisim. It allows the implementation of different models of STI transmission with various levels of complexity and the reconstruction of the complete dynamic sexual partnership network over any time period. A key feature of this framework is that we can trace an individual's partnership history in detail and investigate the outcome of different PN strategies for C. trachomatis. For individual case management, the results suggest that notifying three or more partners from the preceding 18 months yields substantial numbers of new cases. In contrast, the successful treatment of current partners is most important for preventing re-infection of index cases and reducing further transmission of C. trachomatis at the population level. The findings of this study demonstrate the difference between individual and population level outcomes of public health interventions for STIs.
dc.description.numberOfPages1
dc.description.sponsorshipInstitut für Sozial- und Präventivmedizin (ISPM)
dc.identifier.doi10.7892/boris.13974
dc.identifier.isi000313236200109
dc.identifier.pmid23251534
dc.identifier.publisherDOI10.1371/journal.pone.0051438
dc.identifier.urihttps://boris-portal.unibe.ch/handle/20.500.12422/84043
dc.language.isoen
dc.publisherPublic Library of Science
dc.publisher.placeLawrence, Kans.
dc.relation.ispartofPLoS ONE
dc.relation.issn1932-6203
dc.relation.organizationDCD5A442BECFE17DE0405C82790C4DE2
dc.titleIndividual and population level effects of partner notification for Chlamydia trachomatis
dc.typearticle
dspace.entity.typePublication
dspace.file.typetext
oaire.citation.issue12
oaire.citation.startPagee51438
oaire.citation.volume7
oairecerif.author.affiliationInstitut für Sozial- und Präventivmedizin (ISPM)
oairecerif.author.affiliationInstitut für Sozial- und Präventivmedizin (ISPM)
oairecerif.author.affiliationInstitut für Sozial- und Präventivmedizin (ISPM)
oairecerif.author.affiliationInstitut für Sozial- und Präventivmedizin (ISPM)
unibe.contributor.rolecreator
unibe.contributor.rolecreator
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unibe.description.ispublishedpub
unibe.eprints.legacyId13974
unibe.journal.abbrevTitlePLOS ONE
unibe.refereedtrue
unibe.subtype.articlejournal

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