Oxidative Stress in Chronic Liver Disease and Portal Hypertension: Potential of DHA as Nutraceutical.

BORIS DOI
Publisher DOI
PubMed ID
32872239
Description
Chronic liver disease constitutes a growing public health issue worldwide, with no safe and effective enough treatment clinical scenarios. The present review provides an overview of the current knowledge regarding advanced chronic liver disease (ACLD), focusing on the major contributors of its pathophysiology: inflammation, oxidative stress, fibrosis and portal hypertension. We present the benefits of supplementation with docosahexaenoic acid triglycerides (TG-DHA) in other health areas as demonstrated experimentally, and explore its potential as a novel nutraceutical approach for the treatment of ACLD and portal hypertension based on published pre-clinical data.
Date of Publication
2020-08-28
Publication Type
Article
Subject(s)
Keyword(s)
TG-DHA cirrhosis inflammation liver fibrosis omega-3 oxidative stress
Language(s)
en
Contributor(s)
Boyer-Diaz, Zoe
Morata, Paloma
Aristu-Zabalza, Peio
Gibert-Ramos, Albert
Additional Credits
Series
Nutrients
Publisher
MDPI
ISSN
2072-6643
Access(Rights)
open.access
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