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The protease inhibitor alpha-2-macroglobulin-like-1 is the p170 antigen recognized by paraneoplastic pemphigus autoantibodies in human

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cris.virtualsource.author-orcid19a57212-a57f-428a-adb7-3480105942e8
cris.virtualsource.author-orcid11b153eb-ecca-427a-b7fb-c120d0e6d37d
cris.virtualsource.author-orcidbda37f7b-fc2d-4ec1-93c7-fe2d02f9afe9
cris.virtualsource.author-orcidf618d47b-2349-48a6-a9b4-74989a01812f
datacite.rightsopen.access
dc.contributor.authorSchepens, Isabelle
dc.contributor.authorJaunin, Fabienne
dc.contributor.authorBegre, Nadja
dc.contributor.authorLäderach, Ursula
dc.contributor.authorMarcus, Katrin
dc.contributor.authorHashimoto, Takashi
dc.contributor.authorFavre, Bertrand
dc.contributor.authorBorradori, Luca
dc.date.accessioned2024-10-10T20:51:56Z
dc.date.available2024-10-10T20:51:56Z
dc.date.issued2010
dc.description.abstractParaneoplastic pemphigus (PNP) is a devastating autoimmune blistering disease, involving mucocutaneous and internal organs, and associated with underlying neoplasms. PNP is characterized by the production of autoantibodies targeting proteins of the plakin and cadherin families involved in maintenance of cell architecture and tissue cohesion. Nevertheless, the identity of an antigen of Mr 170,000 (p170), thought to be critical in PNP pathogenesis, has remained unknown.
dc.description.numberOfPages1
dc.description.sponsorshipUniversitätsklinik für Dermatologie
dc.description.sponsorshipDepartement Klinische Forschung, Forschungsgruppe Dermatologie
dc.identifier.doi10.7892/boris.2261
dc.identifier.isi000281011600022
dc.identifier.pmid20805888
dc.identifier.publisherDOI10.1371/journal.pone.0012250
dc.identifier.urihttps://boris-portal.unibe.ch/handle/20.500.12422/72967
dc.language.isoen
dc.publisherPublic Library of Science
dc.publisher.placeLawrence, Kans.
dc.relation.ispartofPLoS ONE
dc.relation.issn1932-6203
dc.relation.organizationDCD5A442C465E17DE0405C82790C4DE2
dc.relation.organizationDCD5A442BAD9E17DE0405C82790C4DE2
dc.subject.ddc600 - Technology::610 - Medicine & health
dc.titleThe protease inhibitor alpha-2-macroglobulin-like-1 is the p170 antigen recognized by paraneoplastic pemphigus autoantibodies in human
dc.typearticle
dspace.entity.typePublication
dspace.file.typetext
oaire.citation.issue8
oaire.citation.startPagee12250
oaire.citation.volume5
oairecerif.author.affiliationUniversitätsklinik für Dermatologie
oairecerif.author.affiliationDepartement Klinische Forschung, Forschungsgruppe Dermatologie
oairecerif.author.affiliationUniversitätsklinik für Dermatologie
oairecerif.author.affiliationUniversitätsklinik für Dermatologie
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unibe.description.ispublishedpub
unibe.eprints.legacyId2261
unibe.journal.abbrevTitlePLOS ONE
unibe.refereedtrue
unibe.subtype.articlejournal

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