IRF4 regulates IL-17A promoter activity and controls RORγt-dependent Th17 colitis in vivo

BORIS DOI
Publisher DOI
PubMed ID
21305677
Description
The transcription factor IRF4 is involved in several T-cell-dependent chronic inflammatory diseases. To elucidate the mechanisms for pathological cytokine production in colitis, we addressed the role of the IRF transcription factors in human inflammatory bowel disease (IBD) and experimental colitis.
Date of Publication
2011
Publication Type
Article
Language(s)
en
Contributor(s)
Mudter, Jonas
Yu, Jingling
Zufferey, Christel
Brüstle, Anne
Wirtz, Stefan
Weigmann, Benno
Hoffman, Arthur
Galle, Peter R
Lehr, Hans A
Lohoff, Michael
Neurath, Markus F
Additional Credits
Series
Inflammatory bowel diseases
Publisher
Lippincott Williams & Wilkins
ISSN
1078-0998
Access(Rights)
restricted
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