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  3. Development and Pilot Testing of a Novel Electromechanical Device to Measure Wrist Rigidity in Parkinson’s Disease
 

Development and Pilot Testing of a Novel Electromechanical Device to Measure Wrist Rigidity in Parkinson’s Disease

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BORIS DOI
10.7892/boris.122007
Publisher DOI
10.1109/EMBC.2018.8513422
PubMed ID
30441438
Description
Quantitative assessment of the muscle tone is important when studying patients with neurological disorders such as Parkinson's disease (PD). For the assessment of therapeutic progress, quantitative and objective outcome measures are needed. This article presents a novel electromechanical device to monitor the quantitative rigidity of the wrist joint against passive movement. The novel device is equipped with an electrical motor to move the wrist joint in a flexion-extension manner with different velocity profiles. The accuracy of the device was measured in terms of position, velocity and torque accuracy. The feasibility of the measurement procedure was tested in a pilot study with four PD patients and 12 healthy controls (HC), at velocities of 10 °/s,50 °/s, and 100 °/s. {The position and velocity of the developed device were (0.005 ± 0.105)° and (0.734 ±0.276) °/s, unloaded, and (0.003 ± 0.113) ° and (0.013 ± 0.038) °/s, loaded with a relaxed arm, respectively. The torque accuracy was (15.029 ± 2.235) mNm. The comparison of the median rigidity between the PD patients and HC showed significant differences at all tested velocities, during both flexion and extension movements. This device proved to have sufficient accuracy and sensitivity to precisely measure the interaction torque at the wrist joint and to differentiate PD rigidity from normal muscle tone. The device, thus provides a quantitative and objective measure of rigidity in PD.
Date of Publication
2018-07
Publication Type
Conference Item
Subject(s)
500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health
600 Technology > 620 Engineering
Language(s)
en
Contributor(s)
Zito, Giuseppe Angelo
Universitätsklinik für Neurologie
Gerber, Stephan Moreno
ARTORG Center - Gerontechnology and Rehabilitation
ARTORG Center for Biomedical Engineering Research
Urwyler-Harischandra, Prabithaorcid-logo
Universitätsklinik für Neurologie
ARTORG Center - Gerontechnology and Rehabilitation
Shamsollahi, Mohammad Javad
Dekanat der Medizinischen Fakultät
ARTORG Center - Spine Research Center (SRC)
ARTORG Center - Gerontechnology and Rehabilitation
Pal, Natassja
Benninger, David
Nef, Tobiasorcid-logo
ARTORG Center - Gerontechnology and Rehabilitation
Additional Credits
Universitätsklinik für Neurologie
Dekanat der Medizinischen Fakultät
ARTORG Center - Gerontechnology and Rehabilitation
Series
International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Publisher
IEEE
ISSN
1558-4615
ISBN
978-1-5386-3646-6
Title of Event
2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Access(Rights)
restricted
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