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  3. The influence of different osteosynthesis configurations with locking compression plates (LCP) on stability and fracture healing after an oblique 45° angle osteotomy
 

The influence of different osteosynthesis configurations with locking compression plates (LCP) on stability and fracture healing after an oblique 45° angle osteotomy

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BORIS DOI
10.7892/boris.74292
Date of Publication
2012
Publication Type
Article
Division/Institute

Institut für chirurgi...

Author
Plecko, Michael
Lagerpusch, Nico
Pegel, Birthe
Andermatt, Daniel
Frigg, Robert
Koch, Rudolf
Sidler, Michèle
Kronen, Peter
Klein, Karina
Nuss, Katja
Gédet, Philippe
Institut für chirurgische Technologien und Biomechanik (ISTB)
Bürki, Alexander
Institut für chirurgische Technologien und Biomechanik (ISTB)
Ferguson, Stephen John
Institut für chirurgische Technologien und Biomechanik (ISTB)
Stoeckle, Ulrich
Auer, Jörg A.
von Rechenberg, Brigitte
Subject(s)

500 - Science::570 - ...

600 - Technology::610...

Series
Injury - international journal of the care of the injured
ISSN or ISBN (if monograph)
0020-1383
Publisher
Elsevier
Language
English
Publisher DOI
10.1016/j.injury.2011.12.016
PubMed ID
22284334
Description
Background
Locking compression plates are used in various configurations with lack of detailed information on consequent bone healing.

Study design
In this in vivo study in sheep 5 different applications of locking compression plate (LCP) were tested using a 45° oblique osteotomy simulating simple fracture pattern. 60 Swiss Alpine sheep where assigned to 5 different groups with 12 sheep each (Group 1: interfragmentary lag screw and an LCP fixed with standard cortex screws as neutralisation plate; Group 2: interfragmentary lag screw and LCP with locking head screws; Group 3: compression plate technique (hybrid construct); Group 4: internal fixator without fracture gap; Group 5: internal fixator with 3 mm gap at the osteotomy site). One half of each group (6 sheep) was monitored for 6 weeks, and the other half (6 sheep) where followed for 12 weeks.

Methods
X-rays at 3, 6, 9 and 12 weeks were performed to monitor the healing process. After sacrifice operated tibiae were tested biomechanically for nondestructive torsion and compared to the tibia of the healthy opposite side. After testing specimens were processed for microradiography, histology, histomorphometry and assessment of calcium deposition by fluorescence microscopy.

Results
In all groups bone healing occurred without complications. Stiffness in biomechanical testing showed a tendency for higher values in G2 but results were not statistically significant. Values for G5 were significantly lower after 6 weeks, but after 12 weeks values had improved to comparable results. For all groups, except G3, stiffness values improved between 6 and 12 weeks. Histomorphometrical data demonstrate endosteal callus to be more marked in G2 at 6 weeks.

Discussion and conclusion
All five configurations resulted in undisturbed bone healing and are considered safe for clinical application.
Handle
https://boris-portal.unibe.ch/handle/20.500.12422/136826
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1-s2.0-S0020138311006103-main.pdftextAdobe PDF1.51 MBpublisherpublished restricted
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